Standard models of episodic memory focus on hippocampal–parahippocampal interactions,
with the neocortex supplying sensory information and providing a final repository of …

Recent studies using transgenic mice lacking NMDA receptors in the hippocampus
challenge the long-standing hypothesis that hippocampal long-term potentiation-like …

The hippocampus plays a critical role in goal-directed navigation. Across different
environments, however, hippocampal maps are randomized, making it unclear how goal …

Maneuvering safely through the environment is central to survival of almost all species. The
ability to do this depends on learning and remembering locations. This capacity is encoded …

The formation and retrieval of a memory is thought to be accomplished by activation and
reactivation, respectively, of the memory-holding cells (engram cells) by a common set of …

A model of the neuropsychology of anxiety is proposed. The model is based in the first
instance upon an analysis of the behavioural effects of the antianxiety drugs …

Considers the role of the hippocampus in memory function. A central thesis is that work with
rats, monkeys, and humans (which has sometimes seemed to proceed independently in 3 …

Damage to the hippocampal system disrupts recent memory but leaves remote memory
intact. The account presented here suggests that memories are first stored via synaptic …

Studies of human amnesia and studies of an animal model of human amnesia in the
monkey have identified the anatomical components of the brain system for memory in the …

Abstract Lynch, MA. Long-Term Potentiation and Memory. Physiol Rev 84: 87–136, 2004;
10.1152/physrev. 00014.2003.—One of the most significant challenges in neuroscience is to …