Xanthones or 9H-xanthen-9-ones (dibenzo-γ-pirone) comprise an important class of
oxygenated heterocycles whose role is well-known in Medicinal Chemistry. The biological …

Hepatitis C virus (HCV) is a global public health problem in correctional settings. The
International Network on Health and Hepatitis in Substance Users–Prisons Network is a …

Digestion of hemoglobin in the food vacuole of the malaria parasite produces very high
quantities of redox active toxic free heme. Hemozoin (β-hematin) formation is a unique …

A class of hybrid molecules which we term 'reversed chloroquines'(RCQs) was designed,
and a prototype molecule, N '-(7-chloroquinolin-4-yl)-N-[3-(10, 11-dihydrodibenzo [b, f] …

Recent initiatives to develop more effective and affordable drugs, controlling mosquitoes
and development of a preventative vaccine have been launched with the goal of completely …

Four new xanthones, butyraxanthones A− D (1− 4), were isolated from the stem bark of
Pentadesma butyracea, together with six known xanthones (5− 10) and a triterpenoid …

Significance: Parasitic diseases affect hundreds of millions of people worldwide and
represent major health problems. Treatment is becoming extremely difficult due to the …

The aim of this review is to collect, systematize and contrast the many rccent advances in
xanthones' biochemistry and biology. Advances in understanding xanthones” antirnicrobial …

Improving the solubility of polysubstituted 1, 4-naphthoquinone derivatives was achieved by
introducing nitrogen in two different positions of the naphthoquinone core, at C-5 and at C-8 …

2-Aminopyrimidine based 4-aminoquinolines were synthesized using an efficacious
protocol. Some of the compounds showed in vitro anti-plasmodial activity against drug …