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Behavioral assessment of sensory, motor, emotion, and cognition in rodent models of intracerebral hemorrhage
Intracerebral hemorrhage (ICH) is the second most common type of stroke and has one of
the highest fatality rates of any disease. There are many clinical signs and symptoms after …
the highest fatality rates of any disease. There are many clinical signs and symptoms after …
Factors influencing behavior in the forced swim test
The forced swim test (FST) is a behavioral test in rodents which was developed in 1978 by
Porsolt and colleagues as a model for predicting the clinical efficacy of antidepressant …
Porsolt and colleagues as a model for predicting the clinical efficacy of antidepressant …
[HTML][HTML] Animal models as tools to study the pathophysiology of depression
The incidence of depressive illness is high worldwide, and the inadequacy of currently
available drug treatments contributes to the significant health burden associated with …
available drug treatments contributes to the significant health burden associated with …
The microbiome-gut-brain axis and resilience to develo** anxiety or depression under stress
Episodes of depression and anxiety commonly follow the experience of stress, however not
everyone who experiences stress develops a mood disorder. Individuals who are able to …
everyone who experiences stress develops a mood disorder. Individuals who are able to …
[HTML][HTML] Stress, sensitive periods, and substance abuse
Research on the inter-relationship between drug abuse and social stress has primarily
focused on the role of stress exposure during adulthood and more recently, adolescence …
focused on the role of stress exposure during adulthood and more recently, adolescence …
Exposure to early adversity: Points of cross-species translation that can lead to improved understanding of depression
The relationship between developmental exposure to adversity and affective disorders is
reviewed. Adversity discussed herein includes physical and sexual abuse, neglect, or loss of …
reviewed. Adversity discussed herein includes physical and sexual abuse, neglect, or loss of …
Melatonin and neurotrophins NT-3, BDNF, NGF in patients with varying levels of depression severity
Background Disrupted circadian rhythm of melatonin secretion in depression shows a
relationship with the exacerbation of inflammatory processes. Proinflammatory mechanisms …
relationship with the exacerbation of inflammatory processes. Proinflammatory mechanisms …
Nerve growth factor, stress and diseases
Current Medicinal Chemistry Page 1 Current Medicinal Chemistry Current Medicinal
Chemistry ISSN: 0929-8673 eISSN: 1875-533X The International Journal for Timely In-depth …
Chemistry ISSN: 0929-8673 eISSN: 1875-533X The International Journal for Timely In-depth …
Early maternal deprivation induces microglial activation, alters glial fibrillary acidic protein immunoreactivity and indoleamine 2, 3-dioxygenase during the …
Maternal deprivation (MD) induces behavioral changes and impacts brain circuits that could
be associated with the pathophysiology of depression. This study investigated the markers …
be associated with the pathophysiology of depression. This study investigated the markers …
Environmental enrichment improves lifelong persistent behavioral and epigenetic changes induced by early-life stress
LA Borba, LDR Broseghini, LM Manosso… - Journal of psychiatric …, 2021 - Elsevier
This study aimed to evaluate the effects of environmental enrichment (EE) in Wistar rats
subjected to maternal deprivation (MD). MD was performed in the first post-natal days (PND) …
subjected to maternal deprivation (MD). MD was performed in the first post-natal days (PND) …