Paradoxical tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS) was first
described almost two decades ago. We undertook this systematic review and meta-analysis …

Tuberculosis (TB) remains one of the deadliest infectious diseases responsible for millions
of deaths annually across the world. In this paper we present a general overview of TB …

BACKGROUND: Adverse effects (AE) to TB treatment cause morbidity, mortality and
treatment interruption. The aim of these clinical standards is to encourage best practise for …

Objective To determine and describe the factors influencing treatment default of tuberculosis
(TB) patients in the Free State Province of South Africa. Methods A retrospective records …

Background Drug-induced liver injury (DILI) is a common complication of tuberculosis
treatment. We utilised data from the REMoxTB clinical trial to describe the incidence of …

This review focusses on paradoxical reactions occurring during the treatment of tuberculous
meningitis (TBM) in human immunodeficiency virus-negative cases. A paradoxical reaction …

Background Higher than standard doses of rifampicin could improve the treatment outcome
of drug-susceptible tuberculosis without compromising the safety of patients. Methods We …

Background Elderly persons have the highest rates of tuberculosis (TB) in the United States
compared to all other age groups. A systematic literature review was conducted to determine …

The HIV-associated tuberculosis (TB) epidemic remains a huge challenge to public health in
resource-limited settings. Reducing the nearly 0.5 million deaths that result each year has …

Background The success of tuberculosis treatment relies on patients adhering to their
medication regimen consistently. However, adherence levels tend to decrease among …