Chemically engineered immune cell‐derived microrobots and biomimetic nanoparticles: emerging biodiagnostic and therapeutic tools

LP Jahromi, MA Shahbazi, A Maleki, A Azadi… - Advanced …, 2021 - Wiley Online Library
Over the past decades, considerable attention has been dedicated to the exploitation of
diverse immune cells as therapeutic and/or diagnostic cell‐based microrobots for hard‐to …

Personalized nanovaccines for treating solid cancer metastases

T Feng, J Hu, J Wen, Z Qian, G Che, Q Zhou… - Journal of Hematology & …, 2024 - Springer
Cancer vaccines have garnered attention as a potential treatment for cancer metastases.
Nevertheless, the clinical response rate to vaccines remains< 30%. Nanoparticles stabilize …

Engineering nano‐therapeutics to boost adoptive cell therapy for cancer treatment

C Zheng, J Zhang, HF Chan, H Hu, S Lv, N Na… - Small …, 2021 - Wiley Online Library
Although adoptive transfer of therapeutic cells to cancer patients is demonstrated with great
success and fortunately approved for the treatment of leukemia and B‐cell lymphoma …

Magnetic Delivery of Antigen‐Loaded Magnetic Liposomes for Active Lymph Node Targeting and Enhanced Anti‐Tumor Immunity

J Sheng, Y Liu, H Ding, L Wu, L Liu, G Si… - Advanced …, 2023 - Wiley Online Library
Therapeutic cancer vaccines offer the greatest advantage of enhancing antigen‐specific
immunity against tumors, particularly for immunogenic tumors, such as melanoma. However …

[HTML][HTML] Micro/nanosystems for magnetic targeted delivery of bioagents

F Garello, Y Svenskaya, B Parakhonskiy, M Filippi - Pharmaceutics, 2022 - mdpi.com
Targeted delivery of pharmaceuticals is promising for efficient disease treatment and
reduction in adverse effects. Nano or microstructured magnetic materials with strong …

[HTML][HTML] Improving the efficacy of magnetic nanoparticle-mediated hyperthermia using trapezoidal pulsed electromagnetic fields as an in vitro anticancer treatment in …

L Souiade, J Domingo-Diez, C Alcaide… - International Journal of …, 2023 - mdpi.com
Magnetic hyperthermia (MHT) is an oncological therapy that uses magnetic nanoparticles
(MNPs) to generate localized heat under a low-frequency alternating magnetic field (AMF) …

Iron oxide nanoparticle coatings dictate cell outcomes despite the influence of protein coronas

Y Portilla, S Mellid, A Paradela… - … applied materials & …, 2021 - ACS Publications
A critical issue in nanomedicine is to understand the complex dynamics that dictate the
interactions of nanoparticles (NPs) with their biological milieu. The most exposed part of a …

Glycolysis-related gene expression profiling serves as a novel prognosis risk predictor for human hepatocellular carcinoma

L Zhang, Y Li, Y Dai, D Wang, X Wang, Y Cao, W Liu… - Scientific Reports, 2021 - nature.com
Metabolic pattern reconstruction is an important factor in tumor progression. Metabolism of
tumor cells is characterized by abnormal increase in anaerobic glycolysis, regardless of high …

[HTML][HTML] Magnetic nanostructures as emerging therapeutic tools to boost anti-tumour immunity

S Persano, P Das, T Pellegrino - Cancers, 2021 - mdpi.com
Simple Summary Immunotherapy represents an attractive therapeutic option for effective
treatment of different forms of cancers. However, many patients exhibit primary or acquired …

[HTML][HTML] Citrate-coated superparamagnetic iron oxide nanoparticles enable a stable non-spilling loading of T cells and their magnetic accumulation

P Boosz, F Pfister, R Stein, B Friedrich, L Fester, J Band… - Cancers, 2021 - mdpi.com
Simple Summary In cancer patients, adoptive T cell transfer shall increase the number of
circulating cytotoxic T cells to foster anti-tumor immune responses. In solid tumors, however …