Neurodegenerative diseases commonly induce irreversible destruction of central nervous
system (CNS) neuronal networks, resulting in permanent functional impairments. Effective …

At the present, medication of dementia is limited to symptomatic treatments such as the use
of cholinesterase inhibitors. To cure dementia completely, that is regaining neuronal …

A reversed‐phase HPLC method for the simultaneous analysis of nine structurally similar
withanolides, namely, 27‐hydroxy withanone, 17‐hydroxy withaferin A, 17‐hydroxy‐27 …

Cell suspension cultures of Withania somnifera were established in shake flasks and the
effect of different growth regulators (auxins, combination of auxin and cytokinin), inoculum …

Abstract Background Bisphenol A (BPA), a major endocrine disruptor and a xenobiotic
compound is used abundantly in the production of polycarbonate plastics and epoxy resins …

Multiple shoot cultures of two experimental lines of Withania somnifera plants (RS-Selection-
1 and RS-Selection-2) were established using nodal segments as explants. The hormonal …

Background Systemic inflammation driven neuroinflammation is an event which correlates
with pathogenesis of several neurodegenerative diseases. Therefore, targeting peripheral …

Introduction: Alzheimer's disease (AD) is a progressive, neurodegenerative disease that
severely affects individuals' cognitive abilities, memory, and quality of life. It affects the …

Ethnopharmacological relevance Reproductive problems are becoming the most
predominant health care problems in many countries. World Health Organization (WHO), in …

To understand the relationship between the structure and the remarkably diverse
bioactivities reported for withanolides, we obtained withaferin A (WA; 1) and 36 analogues …