Alopecia areata: an update on etiopathogenesis, diagnosis, and management
C Zhou, X Li, C Wang, J Zhang - Clinical Reviews in Allergy & …, 2021 - Springer
Alopecia areata (AA) is a common chronic tissue-specific autoimmune disease, resulting in
hair loss, that affects up to 2% of the general population. The exact pathobiology of AA has …
hair loss, that affects up to 2% of the general population. The exact pathobiology of AA has …
Hair follicle immune privilege and its collapse in alopecia areata
M Bertolini, K McElwee, A Gilhar… - Experimental …, 2020 - Wiley Online Library
Anagen stage hair follicles (HFs) exhibit “immune privilege (IP)” from the level of the bulge
downwards to the bulb. Both passive and active IP mechanisms protect HFs from …
downwards to the bulb. Both passive and active IP mechanisms protect HFs from …
Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition
Alopecia areata (AA) is a common autoimmune disease resulting from damage of the hair
follicle by T cells. The immune pathways required for autoreactive T cell activation in AA are …
follicle by T cells. The immune pathways required for autoreactive T cell activation in AA are …
An overview of JAK/STAT pathways and JAK inhibition in alopecia areata
Alopecia Areata (AA) is a common autoimmune disease characterized by non-scarring hair
loss ranging from patches on the scalp to complete hair loss involving the entire body …
loss ranging from patches on the scalp to complete hair loss involving the entire body …
Alopecia areata: a review of disease pathogenesis
Background Alopecia areata is a disorder that results in nonscarring hair loss. The
psychological impact can be significant, leading to feelings of depression and social …
psychological impact can be significant, leading to feelings of depression and social …
Alopecia areata: A multifactorial autoimmune condition
T Simakou, JP Butcher, S Reid, FL Henriquez - Journal of autoimmunity, 2019 - Elsevier
Alopecia areata is an autoimmune disease that results in non-scarring hair loss, and it is
clinically characterised by small patches of baldness on the scalp and/or around the body. It …
clinically characterised by small patches of baldness on the scalp and/or around the body. It …
Targeting the Janus kinase family in autoimmune skin diseases
Autoimmune skin diseases are characterized by significant local and systemic inflammation
that is largely mediated by the Janus kinase (JAK)–signal transducer and activator of …
that is largely mediated by the Janus kinase (JAK)–signal transducer and activator of …
Phase 2a randomized clinical trial of dupilumab (anti‐IL‐4Rα) for alopecia areata patients
Background Treatments for alopecia areata (AA) patients with extensive scalp hair loss are
limited, and recent evidence supports a role for type 2 T‐cell (Th2)‐immune response in AA …
limited, and recent evidence supports a role for type 2 T‐cell (Th2)‐immune response in AA …
Baricitinib for the treatment of alopecia areata
E Freitas, E Guttman-Yassky, T Torres - Drugs, 2023 - Springer
Alopecia areata (AA) is a relapsing, chronic, immune-mediated disease characterized by
nonscarring, inflammatory hair loss that can affect any hair-bearing site. AA clinical …
nonscarring, inflammatory hair loss that can affect any hair-bearing site. AA clinical …
Zinc and skin disorders
Y Ogawa, M Kinoshita, S Shimada, T Kawamura - Nutrients, 2018 - mdpi.com
The skin is the third most zinc (Zn)-abundant tissue in the body. The skin consists of the
epidermis, dermis, and subcutaneous tissue, and each fraction is composed of various types …
epidermis, dermis, and subcutaneous tissue, and each fraction is composed of various types …