Half a century of amyloids: past, present and future

PC Ke, R Zhou, LC Serpell, R Riek… - Chemical Society …, 2020 - pubs.rsc.org
Amyloid diseases are global epidemics with profound health, social and economic
implications and yet remain without a cure. This dire situation calls for research into the …

Self-assembling peptide and protein amyloids: from structure to tailored function in nanotechnology

G Wei, Z Su, NP Reynolds, P Arosio… - Chemical Society …, 2017 - pubs.rsc.org
Self-assembled peptide and protein amyloid nanostructures have traditionally been
considered only as pathological aggregates implicated in human neurodegenerative …

[HTML][HTML] Advances in develo** therapeutic strategies for Alzheimer's disease

TT Nguyen, TTD Nguyen, TKO Nguyen, TK Vo - Biomedicine & …, 2021 - Elsevier
Alzheimer's disease (AD) is a progressive deterioration of brain function, initially
characterized by cognitive deficits, with loss of recent memory and language ability …

Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy

I Javed, G Peng, Y **ng, T Yu, M Zhao… - Nature …, 2019 - nature.com
Alzheimer's disease (AD) is the most prevalent form of neurodegenerative disorders, yet no
major breakthroughs have been made in AD human trials and the disease remains a …

The viral protein corona directs viral pathogenesis and amyloid aggregation

K Ezzat, M Pernemalm, S Pålsson, TC Roberts… - Nature …, 2019 - nature.com
Artificial nanoparticles accumulate a protein corona layer in biological fluids, which
significantly influences their bioactivity. As nanosized obligate intracellular parasites, viruses …

Mitigation of amyloidosis with nanomaterials

PC Ke, EH Pilkington, Y Sun, I Javed… - Advanced …, 2020 - Wiley Online Library
Amyloidosis is a biophysical phenomenon of protein aggregation with biological and
pathogenic implications. Among the various strategies developed to date, nanomaterials …

Impact of nanoparticles on amyloid peptide and protein aggregation: a review with a focus on gold nanoparticles

T John, A Gladytz, C Kubeil, LL Martin, HJ Risselada… - Nanoscale, 2018 - pubs.rsc.org
Society is increasingly exposed to nanoparticles as they are ubiquitous in nature and
introduced as man-made air pollutants and as functional ingredients in cosmetic products as …

Bioengineered amyloid peptide for rapid screening of inhibitors against main protease of SARS-CoV-2

D Lee, HG Jung, D Park, J Bang, DY Cheong… - Nature …, 2024 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) has evoked a worldwide pandemic. As the …

The size-effect of gold nanoparticles and nanoclusters in the inhibition of amyloid-β fibrillation

G Gao, M Zhang, D Gong, R Chen, X Hu, T Sun - Nanoscale, 2017 - pubs.rsc.org
A significant pathological signature of Alzheimer's disease (AD) is the deposition of amyloid-
β (Aβ) plaques in the brain and the synaptic dysfunction and neurodegeneration associated …

Graphene quantum dots against human IAPP aggregation and toxicity in vivo

M Wang, Y Sun, X Cao, G Peng, I Javed, A Kakinen… - Nanoscale, 2018 - pubs.rsc.org
The development of biocompatible nanomaterials has become a new frontier in the
detection, treatment and prevention of human amyloid diseases. Here we demonstrated the …