Advancing human gut microbiota research by considering gut transit time

N Procházková, G Falony, LO Dragsted, TR Licht… - Gut, 2023 - gut.bmj.com
Accumulating evidence indicates that gut transit time is a key factor in sha** the gut
microbiota composition and activity, which are linked to human health. Both population-wide …

Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention

M Picon‐Ruiz, C Morata‐Tarifa… - CA: a cancer journal …, 2017 - Wiley Online Library
Answer questions and earn CME/CNE Recent decades have seen an unprecedented rise in
obesity, and the health impact thereof is increasingly evident. In 2014, worldwide, more than …

Obesity and breast cancer: a paradoxical and controversial relationship influenced by menopausal status

L García-Estévez, J Cortés, S Pérez, I Calvo… - Frontiers in …, 2021 - frontiersin.org
Breast cancer is the most common tumor in women worldwide, and an increasing public
health concern. Knowledge of both protective and negative risk factors is essential for a …

[HTML][HTML] Gut microbial β-glucuronidases reactivate estrogens as components of the estrobolome that reactivate estrogens

SM Ervin, H Li, L Lim, LR Roberts, X Liang… - Journal of Biological …, 2019 - Elsevier
Gut microbial β-glucuronidase (GUS) enzymes have been suggested to be involved in the
estrobolome, the collection of microbial reactions involving estrogens. Furthermore, bacterial …

Adiposity and cancer risk: new mechanistic insights from epidemiology

AG Renehan, M Zwahlen, M Egger - Nature Reviews Cancer, 2015 - nature.com
Excess body adiposity, commonly expressed as body mass index (BMI), is a risk factor for
many common adult cancers. Over the past decade, epidemiological data have shown that …

Obesity as a major risk factor for cancer

G De Pergola, F Silvestris - Journal of obesity, 2013 - Wiley Online Library
The number of cancer cases caused by being obese is estimated to be 20% with the
increased risk of malignancies being influenced by diet, weight change, and body fat …

The gut microbiota in breast cancer development and treatment: The good, the bad, and the useful!

D Nandi, S Parida, D Sharma - Gut Microbes, 2023 - Taylor & Francis
Regardless of the global progress in early diagnosis and novel therapeutic regimens, breast
carcinoma poses a devastating threat, and the advances are somewhat marred by high …

Androgen receptor function and targeted therapeutics across breast cancer subtypes

EA Kolyvas, C Caldas, K Kelly, SS Ahmad - Breast Cancer Research, 2022 - Springer
Despite significant progress in breast cancer (BC) therapy, it is globally the most commonly
diagnosed cancer and leads to the death of over 650,000 women annually. Androgen …

Toward precision medicine: building a knowledge network for biomedical research and a new taxonomy of disease

National Research Council, Division on Earth… - 2011 - books.google.com
Motivated by the explosion of molecular data on humans-particularly data associated with
individual patients-and the sense that there are large, as-yet-untapped opportunities to use …

Estrogen metabolism and breast cancer

H Samavat, MS Kurzer - Cancer letters, 2015 - Elsevier
There is currently accumulating evidence that endogenous estrogens play a critical role in
the development of breast cancer. Estrogens and their metabolites have been studied in …