Next-generation sequencing: insights to advance clinical investigations of the microbiome

CR Wensel, JL Pluznick, SL Salzberg, CL Sears - The Journal of clinical …, 2022 - jci.org
Next-generation sequencing (NGS) technology has advanced our understanding of the
human microbiome by allowing for the discovery and characterization of unculturable …

Environmental DNA metabarcoding: Transforming how we survey animal and plant communities

K Deiner, HM Bik, E Mächler, M Seymour… - Molecular …, 2017 - Wiley Online Library
The genomic revolution has fundamentally changed how we survey biodiversity on earth.
High‐throughput sequencing (“HTS”) platforms now enable the rapid sequencing of DNA …

Nonpathogenic Pseudomonas syringae derivatives and its metabolites trigger the plant “cry for help” response to assemble disease suppressing and growth …

Y Liu, H Zhang, J Wang, W Gao, X Sun, Q **ong… - Nature …, 2024 - nature.com
Plants are capable of assembling beneficial rhizomicrobiomes through a “cry for help”
mechanism upon pathogen infestation; however, it remains unknown whether we can use …

Large-scale association analyses identify host factors influencing human gut microbiome composition

A Kurilshikov, C Medina-Gomez, R Bacigalupe… - Nature …, 2021 - nature.com
To study the effect of host genetics on gut microbiome composition, the MiBioGen
consortium curated and analyzed genome-wide genotypes and 16S fecal microbiome data …

RESCRIPt: Reproducible sequence taxonomy reference database management

MS Robeson, DR O'Rourke, BD Kaehler… - PLoS computational …, 2021 - journals.plos.org
Nucleotide sequence and taxonomy reference databases are critical resources for
widespread applications including marker-gene and metagenome sequencing for …

Evaluation of 16S rRNA gene sequencing for species and strain-level microbiome analysis

JS Johnson, DJ Spakowicz, BY Hong… - Nature …, 2019 - nature.com
The 16S rRNA gene has been a mainstay of sequence-based bacterial analysis for
decades. However, high-throughput sequencing of the full gene has only recently become a …

Characteristics of gut microbiota in people with obesity

M Duan, Y Wang, Q Zhang, R Zou, M Guo, H Zheng - Plos one, 2021 - journals.plos.org
Background Obesity is the cause of cardiovascular diseases and other diseases, leading to
increased medical costs, and causing a great burden to individuals, families and society …

Endogenous murine microbiota member Faecalibaculum rodentium and its human homologue protect from intestinal tumour growth

E Zagato, C Pozzi, A Bertocchi, T Schioppa… - Nature …, 2020 - nature.com
The microbiota has been shown to promote intestinal tumourigenesis, but a possible anti-
tumourigenic effect has also been postulated. Here, we demonstrate that changes in the …

Rare microbial taxa as the major drivers of ecosystem multifunctionality in long-term fertilized soils

QL Chen, J Ding, D Zhu, HW Hu… - Soil Biology and …, 2020 - Elsevier
Soil microbial communities play an essential role in driving multiple functions (ie,
multifunctionality) that are central to the global biogeochemical cycles. Long-term fertilization …

Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system

G Chevalier, E Siopi, L Guenin-Macé, M Pascal… - Nature …, 2020 - nature.com
Depression is the leading cause of disability worldwide. Recent observations have revealed
an association between mood disorders and alterations of the intestinal microbiota. Here …