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Next-generation sequencing: insights to advance clinical investigations of the microbiome
Next-generation sequencing (NGS) technology has advanced our understanding of the
human microbiome by allowing for the discovery and characterization of unculturable …
human microbiome by allowing for the discovery and characterization of unculturable …
Environmental DNA metabarcoding: Transforming how we survey animal and plant communities
The genomic revolution has fundamentally changed how we survey biodiversity on earth.
High‐throughput sequencing (“HTS”) platforms now enable the rapid sequencing of DNA …
High‐throughput sequencing (“HTS”) platforms now enable the rapid sequencing of DNA …
Nonpathogenic Pseudomonas syringae derivatives and its metabolites trigger the plant “cry for help” response to assemble disease suppressing and growth …
Y Liu, H Zhang, J Wang, W Gao, X Sun, Q **ong… - Nature …, 2024 - nature.com
Plants are capable of assembling beneficial rhizomicrobiomes through a “cry for help”
mechanism upon pathogen infestation; however, it remains unknown whether we can use …
mechanism upon pathogen infestation; however, it remains unknown whether we can use …
Large-scale association analyses identify host factors influencing human gut microbiome composition
To study the effect of host genetics on gut microbiome composition, the MiBioGen
consortium curated and analyzed genome-wide genotypes and 16S fecal microbiome data …
consortium curated and analyzed genome-wide genotypes and 16S fecal microbiome data …
RESCRIPt: Reproducible sequence taxonomy reference database management
Nucleotide sequence and taxonomy reference databases are critical resources for
widespread applications including marker-gene and metagenome sequencing for …
widespread applications including marker-gene and metagenome sequencing for …
Evaluation of 16S rRNA gene sequencing for species and strain-level microbiome analysis
The 16S rRNA gene has been a mainstay of sequence-based bacterial analysis for
decades. However, high-throughput sequencing of the full gene has only recently become a …
decades. However, high-throughput sequencing of the full gene has only recently become a …
Characteristics of gut microbiota in people with obesity
Background Obesity is the cause of cardiovascular diseases and other diseases, leading to
increased medical costs, and causing a great burden to individuals, families and society …
increased medical costs, and causing a great burden to individuals, families and society …
Endogenous murine microbiota member Faecalibaculum rodentium and its human homologue protect from intestinal tumour growth
The microbiota has been shown to promote intestinal tumourigenesis, but a possible anti-
tumourigenic effect has also been postulated. Here, we demonstrate that changes in the …
tumourigenic effect has also been postulated. Here, we demonstrate that changes in the …
Rare microbial taxa as the major drivers of ecosystem multifunctionality in long-term fertilized soils
Soil microbial communities play an essential role in driving multiple functions (ie,
multifunctionality) that are central to the global biogeochemical cycles. Long-term fertilization …
multifunctionality) that are central to the global biogeochemical cycles. Long-term fertilization …
Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system
G Chevalier, E Siopi, L Guenin-Macé, M Pascal… - Nature …, 2020 - nature.com
Depression is the leading cause of disability worldwide. Recent observations have revealed
an association between mood disorders and alterations of the intestinal microbiota. Here …
an association between mood disorders and alterations of the intestinal microbiota. Here …