Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders

MA Katzman, P Bleau, P Blier, P Chokka, K Kjernisted… - BMC psychiatry, 2014 - Springer
Background Anxiety and related disorders are among the most common mental disorders,
with lifetime prevalence reportedly as high as 31%. Unfortunately, anxiety disorders are …

[HTML][HTML] Addressing the side effects of contemporary antidepressant drugs: a comprehensive review

SM Wang, C Han, WM Bahk, SJ Lee… - Chonnam medical …, 2018 - synapse.koreamed.org
Randomized trials have shown that selective serotonin reuptake inhibitors (SSRIs) and
serotonin-norepinephrine reuptake inhibitors (SNRIs) have better safety profiles than …

Gastrointestinal side effects associated with antidepressant treatments in patients with major depressive disorder: a systematic review and meta-analysis

V Oliva, M Lippi, R Paci, L Del Fabro… - Progress in Neuro …, 2021 - Elsevier
Gastrointestinal side effects (SEs) are frequently observed in patients with major depressive
disorder (MDD) while taking antidepressants and may lead to treatment discontinuation. The …

Canadian Network for Mood and Anxiety Treatments (CANMAT) Clinical guidelines for the management of major depressive disorder in adults.: III. Pharmacotherapy

RW Lam, SH Kennedy, S Grigoriadis… - Journal of affective …, 2009 - Elsevier
BACKGROUND: In 2001, the Canadian Psychiatric Association and the Canadian Network
for Mood and Anxiety Treatments (CANMAT) partnered to produce evidence-based clinical …

[HTML][HTML] Effects of exercise training on anxious–depressive-like behavior in Alzheimer rat

C Wu, L Yang, Y Li, YAN Dong, B Yang… - Medicine and science …, 2020 - ncbi.nlm.nih.gov
PURPOSE This study aimed to examine the effects of treadmill training on anxious-
depressive-like behaviors of transgenic Alzheimer rats in the early stage of Alzheimer's …

[HTML][HTML] Antidepressant-like activities of live and heat-killed Lactobacillus paracasei PS23 in chronic corticosterone-treated mice and possible mechanisms

CL Wei, S Wang, JT Yen, YF Cheng, CL Liao, CC Hsu… - Brain research, 2019 - Elsevier
Emerging evidence indicates that ingestion of specific probiotics, known as “psychobiotics”,
confer beneficial effects on mental health. This study investigated antidepressant-like effects …

Natural products inhibitors of monoamine oxidases—Potential new drug leads for neuroprotection, neurological disorders, and neuroblastoma

ND Chaurasiya, F Leon, I Muhammad, BL Tekwani - Molecules, 2022 - mdpi.com
Monoamine oxidase inhibitors (MAOIs) are an important class of drugs prescribed for
treatment of depression and other neurological disorders. Evidence has suggested that …

Differences in adverse effect reporting in placebo groups in SSRI and tricyclic antidepressant trials: a systematic review and meta-analysis

W Rief, Y Nestoriuc, A von Lilienfeld-Toal, I Dogan… - Drug Safety, 2009 - Springer
Background: Biases in adverse effect reporting in randomized controlled trials (RCTs)[eg
due to investigator expectations or assessment quality] can be quantified by studying the …

Primum Non Nocere: An Evolutionary Analysis of Whether Antidepressants Do More Harm than Good

PW Andrews, JA Thomson Jr, A Amstadter… - Frontiers in …, 2012 - frontiersin.org
Antidepressant medications are the first-line treatment for people meeting current diagnostic
criteria for major depressive disorder. Most antidepressants are designed to perturb the …

Comparative benefits and harms of second-generation antidepressants: background paper for the American College of Physicians

G Gartlehner, BN Gaynes, RA Hansen… - Annals of internal …, 2008 - acpjournals.org
Background: Second-generation antidepressants dominate the management of major
depressive disorder, dysthymia, and subsyndromal depression. Evidence on the …