Sphingolipids (SLs) are common in all eukaryotes, prokaryotes, and viruses, and played a
vital role in human health. They are involved in physiological processes, including …

Many ribonucleases (RNases) are able to inhibit the reproduction of viruses in infected cell
cultures and laboratory animals, but the molecular mechanisms of their antiviral activity …

Programmed cell death and especially necroptosis, a programmed and regulated form of
necrosis, have been recently implicated in the progression and outcomes of influenza in …

Sphingolipids are potent bioactive agents involved in the pathogenesis of various
respiratory bacterial infections. To date, several sphingolipid derivatives are known, but S1P …

Influenza-A virus (IAV) infects yearly an estimated one billion people worldwide, resulting in
300,000–650,000 deaths. Preventive vaccination programs and antiviral medications …

Our previous study showed anti-influenza virus activity in adlay tea prepared from adlay
seeds, naked barley seeds, soybean, and cassia seeds. In this study, we evaluated the anti …

Viruses attempt to create a distinctive cellular environment to favor viral replication and
spread. Recent studies uncovered new functions of the sphingolipid signaling/metabolism …

Respiratory viruses pose a continuing and substantive threat to human health globally. Host
innate and adaptive immune responses are the critical antiviral defense mechanisms to …

We have recently reported that transcription factor Runx3 is required for pulmonary
generation of CD8+ cytotoxic T lymphocytes (CTLs) that play a crucial role in the clearance …

Influenza A virus (IAV) targets airway epithelial cells and exploits the host cell machinery to
replicate, causing respiratory illness in annual epidemics and pandemics of variable …