The nuclear pore complex (NPC) serves as the sole bidirectional gateway of
macromolecules in and out of the nucleus. Owing to its size and complexity (∼ 1,000 protein …

Nuclear pore complexes (NPCs) fuse the inner and outer nuclear membranes to form
channels across the nuclear envelope. They are large macromolecular assemblies with a …

INTRODUCTION The nucleus harbors and protects the genetic information in eukaryotes. It
is surrounded by the nuclear envelope, which separates the nucleoplasm from the cytosol …

INTRODUCTION Cytoplasmic face of the human NPC. Near-atomic composite structure of
the NPC generated by docking high-resolution crystal structures into a cryo‑ET …

Nuclear pore complexes (NPCs) mediate the nucleocytoplasmic transport of
macromolecules. Here we provide a structure of the isolated yeast NPC in which the inner …

INTRODUCTION The nuclear pore complex (NPC) resides on the nuclear envelope (NE)
and mediates nucleocytoplasmic cargo transport. As one of the largest cellular machineries …

Nuclear pore complexes (NPCs) perforate the nuclear envelope and serve as the primary
transport gates for molecular exchange between nucleus and cytoplasm. Strip** the …

Nuclear pore complexes (NPCs) provide a selective passageway for receptor-mediated
active transport between nucleus and cytoplasm, while maintaining the distinct molecular …

INTRODUCTION In eukaryotic cells, the selective bidirectional transport of macromolecules
between the nucleus and cytoplasm occurs through the nuclear pore complex (NPC) …

Nuclear pore complexes (NPCs) fuse the inner and outer membranes of the nuclear
envelope. They comprise hundreds of nucleoporins (Nups) that assemble into multiple …