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Pyridine: the scaffolds with significant clinical diversity
The nitrogen-bearing heterocycle pyridine in its several analogous forms occupies an
important position as a precious source of clinically useful agents in the field of medicinal …
important position as a precious source of clinically useful agents in the field of medicinal …
Roles of pyridine and pyrimidine derivatives as privileged scaffolds in anticancer agents
S Prachayasittikul, R **aew… - Mini Reviews in …, 2017 - benthamdirect.com
Background: Cancer has been considered to be a global health concern due to the impact of
disease on the quality of life. The continual increase of cancer cases as well as the …
disease on the quality of life. The continual increase of cancer cases as well as the …
Design, synthesis and docking studies of novel thiazole derivatives incorporating pyridine moiety and assessment as antimicrobial agents
RE Khidre, IAM Radini - Scientific Reports, 2021 - nature.com
A novel series of substituted 4, 6-dimethyl-2-oxo-1-(thiazol-2-ylamino)-1, 2-dihydropyridine-
3-carbonitrile derivatives 6, 9, 13, 15, and 17 was synthesized in a good to excellent yield …
3-carbonitrile derivatives 6, 9, 13, 15, and 17 was synthesized in a good to excellent yield …
[HTML][HTML] Anticancer and antimicrobial activity of new copper (II) complexes
A Climova, E Pivovarova, M Szczesio, K Gobis… - Journal of Inorganic …, 2023 - Elsevier
In this study, three new organic ligands N′-(benzylidene)-6-chloropyrazine-2-
carbohydrazonamide (L 1), 6-chloro-N′-(4-nitrobenzylidene) picolinohydrazonamide (L 2) …
carbohydrazonamide (L 1), 6-chloro-N′-(4-nitrobenzylidene) picolinohydrazonamide (L 2) …
Antiviral activities of pyridine fused and pyridine containing heterocycles, a review (from 2000 to 2020)
SR Alizadeh, MA Ebrahimzadeh - Mini Reviews in Medicinal …, 2021 - benthamdirect.com
Heterocyclic compounds play a critical role in medicinal chemistry, and many available
drugs contain heterocyclic rings. A six-membered heterocyclic compound, pyridine, showed …
drugs contain heterocyclic rings. A six-membered heterocyclic compound, pyridine, showed …
High therapeutic potential of Spilanthes acmella: a review
V Prachayasittikul, S Prachayasittikul… - EXCLI …, 2013 - pmc.ncbi.nlm.nih.gov
Spilanthes acmella, a well known antitoothache plant with high medicinal usages, has been
recognized as an important medicinal plant and has an increasingly high demand …
recognized as an important medicinal plant and has an increasingly high demand …
Synthesis, anticancer activity and QSAR study of 1, 4-naphthoquinone derivatives
V Prachayasittikul, R **aew… - European Journal of …, 2014 - Elsevier
A series of 2-substituted amino-3-chloro-1, 4-naphthoquinone derivatives (3–12) were
synthesized as anticancer agents and tested against four cancer cell lines including HepG2 …
synthesized as anticancer agents and tested against four cancer cell lines including HepG2 …
Discovery of novel 1, 2, 3-triazole derivatives as anticancer agents using QSAR and in silico structural modification
V Prachayasittikul, R **aew, N Anuwongcharoen… - Springerplus, 2015 - Springer
Considerable attention has been given on the search for novel anticancer drugs with respect
to the disease sequelae on human health and well-being. Triazole is considered to be an …
to the disease sequelae on human health and well-being. Triazole is considered to be an …
One-pot multicomponent synthesis of novel pyridine derivatives for antidiabetic and antiproliferative activities
Background: Due to the close relationship of diabetes with hypertension reported in various
research, a set of pyridine derivatives with US FDA-approved drug cores were designed and …
research, a set of pyridine derivatives with US FDA-approved drug cores were designed and …
Synthesis, molecular docking and in vitro screening of some newly synthesized triazolopyridine, pyridotriazine and pyridine–pyrazole hybrid derivatives
EM Flefel, WI El-Sofany, M El-Shahat, A Naqvi… - Molecules, 2018 - mdpi.com
A series of novel pyridine and fused pyridine derivatives have been prepared starting from 6-
(3, 4-dimethylphenyl)-2-hydrazinyl-4-(thiophen-2-yl)-pyridine-3-carbonitrile 1 which on …
(3, 4-dimethylphenyl)-2-hydrazinyl-4-(thiophen-2-yl)-pyridine-3-carbonitrile 1 which on …