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Synaptic plasticity and mental health: methods, challenges and opportunities
Activity-dependent synaptic plasticity is a ubiquitous property of the nervous system that
allows neurons to communicate and change their connections as a function of past …
allows neurons to communicate and change their connections as a function of past …
Neurofilaments: neurobiological foundations for biomarker applications
Interest in neurofilaments has risen sharply in recent years with recognition of their potential
as biomarkers of brain injury or neurodegeneration in CSF and blood. This is in the context …
as biomarkers of brain injury or neurodegeneration in CSF and blood. This is in the context …
[HTML][HTML] Psychobiotics and the manipulation of bacteria–gut–brain signals
Psychobiotics were previously defined as live bacteria (probiotics) which, when ingested,
confer mental health benefits through interactions with commensal gut bacteria. We expand …
confer mental health benefits through interactions with commensal gut bacteria. We expand …
Anxiety and depression: A top‐down, bottom‐up model of circuit function
DO LeDuke, M Borio, R Miranda… - Annals of the New York …, 2023 - Wiley Online Library
A functional interplay of bottom‐up and top‐down processing allows an individual to
appropriately respond to the dynamic environment around them. These processing …
appropriately respond to the dynamic environment around them. These processing …
Alzheimer's disease and gut microbiota
X Hu, T Wang, F ** - Science China Life Sciences, 2016 - Springer
Alzheimer's disease (AD) is a most common neurodegenerative disorder, which associates
with impaired cognition. Gut microbiota can modulate host brain function and behavior via …
with impaired cognition. Gut microbiota can modulate host brain function and behavior via …
[HTML][HTML] The toxicity and polymorphism of β-amyloid oligomers
Y Huang, R Liu - International journal of molecular sciences, 2020 - mdpi.com
It is widely accepted that β-amyloid oligomers (Aβos) play a key role in the progression of
Alzheimer's disease (AD) by inducing neuron damage and cognitive impairment, but Aβos …
Alzheimer's disease (AD) by inducing neuron damage and cognitive impairment, but Aβos …
Identification of the molecular mechanism of insulin-like growth factor-1 (IGF-1): a promising therapeutic target for neurodegenerative diseases associated with …
A Arjunan, DK Sah, M Woo, J Song - Cell & Bioscience, 2023 - Springer
Neurodegenerative disorders are accompanied by neuronal degeneration and glial
dysfunction, resulting in cognitive, psychomotor, and behavioral impairment. Multiple factors …
dysfunction, resulting in cognitive, psychomotor, and behavioral impairment. Multiple factors …
[HTML][HTML] High intelligence: A risk factor for psychological and physiological overexcitabilities
RI Karpinski, AMK Kolb, NA Tetreault, TB Borowski - Intelligence, 2018 - Elsevier
High intelligence is touted as being predictive of positive outcomes including educational
success and income level. However, little is known about the difficulties experienced among …
success and income level. However, little is known about the difficulties experienced among …
Single-cell multi-cohort dissection of the schizophrenia transcriptome
The complexity and heterogeneity of schizophrenia have hindered mechanistic elucidation
and the development of more effective therapies. Here, we performed single-cell dissection …
and the development of more effective therapies. Here, we performed single-cell dissection …
Polyamines: bio-molecules with diverse functions in plant and human health and disease
Biogenic amines—polyamines (PAs), particularly putrescine, spermidine and spermine are
ubiquitous in all living cells. Their indispensable roles in many biochemical and …
ubiquitous in all living cells. Their indispensable roles in many biochemical and …