Coumarin-derived Hydroxamic Acids as Histone Deacetylase Inhibitors: A Review of Anti-cancer Activities
NQ Khai, TK Vu - Anti-Cancer Agents in Medicinal Chemistry …, 2024 - ingentaconnect.com
Since coumarin and hydroxamic acid compounds are well-known in medicinal chemistry, a
variety of their derivatives have been highlighted due to their potential uses for plentiful …
variety of their derivatives have been highlighted due to their potential uses for plentiful …
Nitrogen containing heterocycles as anticancer agents: a medicinal chemistry perspective
Cancer is one of the major healthcare challenges across the globe. Several anticancer
drugs are available on the market but they either lack specificity or have poor safety, severe …
drugs are available on the market but they either lack specificity or have poor safety, severe …
Exploring diverse frontiers: Advancements of bioactive 4-aminoquinoline-based molecular hybrids in targeted therapeutics and beyond
Amongst heterocyclic compounds, quinoline and its derivatives are advantaged scaffolds
that appear as a significant assembly motif for develo** new drug entities. Aminoquinoline …
that appear as a significant assembly motif for develo** new drug entities. Aminoquinoline …
Ferrocene-based drugs, delivery nanomaterials and fenton mechanism: state of the art, recent developments and prospects
Ferrocene has been the most used organometallic moiety introduced in organic and
bioinorganic drugs to cure cancers and various other diseases. Following several …
bioinorganic drugs to cure cancers and various other diseases. Following several …
Current scenario of pyrazole hybrids with in vivo therapeutic potential against cancers
Z Xu, Y Zhuang, Q Chen - European Journal of Medicinal Chemistry, 2023 - Elsevier
Chemotherapeutics occupy a pivotal role in the medication of different types of cancers, but
the prevalence and mortality rates of cancer remain high. The drug resistance and low …
the prevalence and mortality rates of cancer remain high. The drug resistance and low …
Advances in the greener synthesis of chromopyrimidine derivatives by a multicomponent tandem oxidation process
A hydrophilic cobalt/copper heterogeneous bimetallic catalyst named mTEG-CS-Co/Cu-
Schiff-base/IL was successfully synthesized from chitosan polysaccharide. The new catalyst …
Schiff-base/IL was successfully synthesized from chitosan polysaccharide. The new catalyst …
Recent drug design strategies and identification of key heterocyclic scaffolds for promising anticancer targets
Cancer, a noncommunicable disease, is the leading cause of mortality worldwide and is
anticipated to rise by 75% in the next two decades, reaching approximately 25 million cases …
anticipated to rise by 75% in the next two decades, reaching approximately 25 million cases …
[HTML][HTML] New Schiff bases derived from dimethylpyridine-1, 2, 4-triazole hybrid as cytotoxic agents targeting gastrointestinal cancers: Design, synthesis, biological …
M Strzelecka, B Wiatrak, P Jawień, Ż Czyżnikowska… - Bioorganic …, 2023 - Elsevier
In this research, a series of novel hybrid structures of dimethylpyridine-1, 2, 4-triazole Schiff
bases were designed, synthesized, and evaluated for their in vitro cytotoxic potency on …
bases were designed, synthesized, and evaluated for their in vitro cytotoxic potency on …
Electron-reservoir applications of ferrocenes and other late transition-metal sandwich complexes: Flow batteries, sensing, catalysis, and biomedicine
T Wang, D Astruc - Coordination Chemistry Reviews, 2025 - Elsevier
This review presents the applications of first-row late transition-metal sandwich complexes,
including derivatives of ferrocene, FeCp 2 (Cp= η 5-C 5 H 5), and of salts of cobalticenium …
including derivatives of ferrocene, FeCp 2 (Cp= η 5-C 5 H 5), and of salts of cobalticenium …
Design and synthesis of some novel hybrid molecules based on 4-thiazolidinone bearing pyridine-pyrazole scaffolds: molecular docking and molecular dynamics …
Due to multidrug resistance, microbial infections have become significant on a global level.
As infections caused by several resistant bacteria and fungi severely harm mankind …
As infections caused by several resistant bacteria and fungi severely harm mankind …