[HTML][HTML] Biothermodynamics of viruses from absolute zero (1950) to virothermodynamics (2022)

M Popovic - Vaccines, 2022 - mdpi.com
Biothermodynamics of viruses is among the youngest but most rapidly develo** scientific
disciplines. During the COVID-19 pandemic, it closely followed the results published by …

Never ending story? Evolution of SARS-CoV-2 monitored through Gibbs energies of biosynthesis and antigen-receptor binding of Omicron BQ. 1, BQ. 1.1, XBB and …

M Popovic - Microbial risk analysis, 2023 - Elsevier
RNA viruses exhibit a great tendency to mutate. Mutations occur in the parts of the genome
that encode the spike glycoprotein and less often in the rest of the genome. This is why …

[HTML][HTML] Omicron BA. 2.75 subvariant of SARS-CoV-2 is expected to have the greatest infectivity compared with the competing BA. 2 and BA. 5, due to most negative …

M Popovic - BioTech, 2022 - mdpi.com
Omicron BA. 2.75 may become the next globally dominant strain of COVID-19 in 2022. The
BA. 2.75 sub-variant has acquired more mutations (9) in spike protein and other genes of …

[HTML][HTML] Omicron BA. 2.75 sublineage (centaurus) follows the expectations of the evolution theory: less negative gibbs energy of biosynthesis indicates decreased …

M Popovic - Microbiology Research, 2022 - mdpi.com
SARS-CoV-2 belongs to the group of RNA viruses with a pronounced tendency to mutate.
Omicron BA. 2.75 is a subvariant believed to be able to suppress the currently dominant BA …

Atom counting method for determining elemental composition of viruses and its applications in biothermodynamics and environmental science

M Popovic - Computational biology and chemistry, 2022 - Elsevier
Quantitative physicochemical perspective on life processes has been a great asset, in
bioengineering and biotechnology. The quantitative physicochemical approach can be …

The SARS-CoV-2 Hydra, a tiny monster from the 21st century: Thermodynamics of the BA. 5.2 and BF. 7 variants

M Popovic - Microbial Risk Analysis, 2023 - Elsevier
SARS-CoV-2 resembles the ancient mythical creature Hydra. Just like with the Hydra, when
one head is cut, it is followed by appearance of two more heads, suppression of one SARS …

COVID infection in 4 steps: thermodynamic considerations reveal how viral mucosal diffusion, target receptor affinity and furin cleavage act in concert to drive the …

M Popovic, JH Martin, RJ Head - Heliyon, 2023 - cell.com
We have developed a mechanistic model of SARS-CoV-2 and SARS-CoV infection,
exploring the relationship between the viral diffusion in the mucosa and viral affinity for the …

A thermodynamic insight into viral infections: do viruses in a lytic cycle hijack cell metabolism due to their low Gibbs energy?

M Popovic, M Minceva - Heliyon, 2020 - cell.com
After adsorption and penetration, a virus hijacks a cell's metabolic machinery and uses it as
a medium for its reproduction and growth through multiplication. Growth is competitive, since …

Assessment of tomato production process by cumulative exergy consumption approach in greenhouse and open field conditions: Case study of Turkey

H Yildizhan, M Taki - Energy, 2018 - Elsevier
Cumulative exergy consumption is an innovative method that can help to evaluate different
energy use problems in crop production process. In this study, cumulative exergy approach …

A step toward precision gerontology: lifespan effects of calorie and protein restriction are consistent with predicted impacts on entropy generation

AS Semerciöz-Oduncuoğlu, SE Mitchell… - Proceedings of the …, 2023 - pnas.org
Understanding aging is a key biological goal. Precision gerontology aims to predict how
long individuals will live under different treatment scenarios. Calorie and protein restriction …