Surface of a particle is inevitably charged. When the particle is surrounded by a fluid a
potential difference arises between the surface and bulk, called zeta potential (ζ) which …

The Electrospray Ionization (ESI) is a soft ionization technique extensively used for
production of gas phase ions (without fragmentation) of thermally labile large …

Abstract I. Introduction 363 II. The Mechanics of ESI‐MS 363 III. Analyte Characteristics and
Selectivity 365 A. Charging the Analyte 366 1. Ionization Through Charge Separation 366 2 …

The most widely used ionization techniques in liquid chromatography–mass spectrometry
(LC–MS) are electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI) …

Ever since the inception of synthetic polymeric materials in the late 19th century, the number
of studies on polymers as well as the complexity of their structures have only increased. The …

Nonpolar regions in biological molecules are investigated as a determining factor governing
their electrospray ionization (ESI) mass spectrometric response. Response is compared for …

In this tutorial, the mechanism and origin of ion suppression will be investigated, as well as
ways to validate the presence, and circumvent or compensate for, the effects in LC-MS.Ion …

Lipids are ubiquitous in the human organism and play essential roles as components of cell
membranes and hormones, for energy storage or as mediators of cell signaling pathways …

Matrix effect on mass spectrometry response was investigated with commercially available
electrospray ionisation (ESI) and atmospheric pressure chemical ionisation (APCI) sources …

The analysis of highly hydrophilic, ionic, and polar compounds has been performed by
HILIC‐ESI‐MS for the last few years. The use of low aqueous/high polar organic solvent …