[PDF][PDF] A review of colorectal cancer research in Malaysia

LK Ghee - Med J Malaysia, 2014 - Citeseer
SUMMARY 105 articles related to colorectal cancer (CRC) were found in a search through a
database dedicated to indexing all original data relevant to medicine published in Malaysia …

Comparison of universal screening in major lynch-associated tumors: a systematic review of literature

G Kunnackal John, V Das Villgran, C Caufield-Noll… - Familial Cancer, 2022 - Springer
Lynch syndrome (LS) is associated with an increased lifetime risk of several cancers
including colorectal (CRC), endometrial (EC), ovarian (OC), urinary (UT) and sebaceous …

Coordinated protein and DNA conformational changes govern mismatch repair initiation by MutS

SJ LeBlanc, JW Gauer, P Hao, BC Case… - Nucleic acids …, 2018 - academic.oup.com
MutS homologs identify base-pairing errors made in DNA during replication and initiate their
repair. In the presence of adenosine triphosphate, MutS induces DNA bending upon …

Mismatch repair deficiency screening in colorectal carcinoma by a four-antibody immunohistochemical panel in Pakistani population and its correlation with …

AA Hashmi, R Ali, ZF Hussain, N Faridi… - World Journal of …, 2017 - Springer
Background Microsatellite instability (MSI) operates as the second major pathway in the
colorectal carcinogenesis. Although genetic testing remains the gold standard for the …

Analysis of the Clinicopathological Characteristics of Stage I–III Colorectal Cancer Patients Deficient in Mismatch Repair Proteins

Y Liang, X Cai, X Zheng, H Yin - OncoTargets and therapy, 2021 - Taylor & Francis
Purpose To investigate the clinicopathological characteristics of stage I–III colorectal cancer
(CRC) patients with deficient mismatch repair (dMMR) protein. Patients and Methods A …

A DNA damage repair gene signature associated with immunotherapy response and clinical prognosis in clear cell renal cell carcinoma

L Peng, J Liang, Q Wang, G Chen - Frontiers in Genetics, 2022 - frontiersin.org
Background: Clear cell renal cell carcinoma (ccRCC) is the most common subtype in renal
cell carcinoma with relatively poor clinical outcomes DNA damage repair genes (DDRGs) as …

Evaluation of the preventive potential of graded dietary inclusion of Hyphaene thebaica (Linn) fruit in rat model of colon carcinogenesis

A Yusuf, OE Odeh, SO Alhassan… - Journal of Food …, 2022 - Wiley Online Library
The preventive effect of Hyphaene thebaica fruit in colon carcinogenesis was evaluated in
Wistar rats at 0, 2.5, 5 and 10% inclusion rates for twelve weeks with concomitant 72‐h intra …

Relationship among mismatch repair deficiency, CDX2 loss, p53 and E-cadherin in colon carcinoma and suitability of using a double panel of mismatch repair …

I Sayar, EM Akbas, A Isik, A Gokce, K Peker… - Polish Journal of …, 2015 - termedia.pl
Biomarkers such as mismatch repair proteins, CDX2, p53, and E-cadherin are blamed for
colon cancers, but the relationships of these biomarkers with each other and with …

Microsatellite instability and loss of heterozygosity detected in middle‑aged patients with sporadic colon cancer: A retrospective study

N Kamat, MA Khidhir, MM Alashari… - Oncology …, 2013 - spandidos-publications.com
Microsatellite instability (MSI) is a mutator phenotype that results from a defective mismatch
repair (MMR) pathway. The present study examined the incidence of MSI and loss of …

A novel Lynch syndrome pedigree bearing germ-line MSH2 missense mutation c.1808A>T (Asp603Val)

R Sekine, K Shimazu, D Nakano… - Japanese Journal of …, 2022 - academic.oup.com
We report the first pedigree of Lynch syndrome bearing a germ-line MSH2 missense
mutation c. 1808A> T (Asp603Val). Until now, this missense mutation, in exon 12 of MSH2 …