Mechanical forces amplify TCR mechanotransduction in T cell activation and function
Adoptive T cell immunotherapies, including engineered T cell receptor (eTCR) and chimeric
antigen receptor (CAR) T cell immunotherapies, have shown efficacy in treating a subset of …
antigen receptor (CAR) T cell immunotherapies, have shown efficacy in treating a subset of …
Mechanically triggered adaptive materials
Adaptive materials, characterized by their dynamic response to external stimuli, undergo
changes in their physical or chemical properties to suit varying environmental conditions …
changes in their physical or chemical properties to suit varying environmental conditions …
Biomechanics in blood cell functions and diseases
J Lin, C Dong, J Wu - Frontiers in Bioengineering and Biotechnology, 2024 - frontiersin.org
The intricate interplay between blood cells and their biomechanical microenvironment is
crucial for the proper functioning of physiological and pathophysiological processes …
crucial for the proper functioning of physiological and pathophysiological processes …
Mechanical control of antigen detection and discrimination by T and B cell receptors
The adaptive immune response is orchestrated by just two cell types: T cells and B cells.
Both cells possess the remarkable ability to recognise virtually any antigen through their …
Both cells possess the remarkable ability to recognise virtually any antigen through their …