Antibiotic perturbations to the gut microbiome
Antibiotic-mediated perturbation of the gut microbiome is associated with numerous
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …
Bench to bedside—new insights into the pathogenesis of necrotizing enterocolitis
Necrotizing enterocolitis (NEC) is the leading cause of death and disability from
gastrointestinal disease in premature infants. Recent discoveries have shed light on a …
gastrointestinal disease in premature infants. Recent discoveries have shed light on a …
inStrain profiles population microdiversity from metagenomic data and sensitively detects shared microbial strains
Coexisting microbial cells of the same species often exhibit genetic variation that can affect
phenotypes ranging from nutrient preference to pathogenicity. Here we present inStrain, a …
phenotypes ranging from nutrient preference to pathogenicity. Here we present inStrain, a …
Human milk oligosaccharide DSLNT and gut microbiome in preterm infants predicts necrotising enterocolitis
Objective Necrotising enterocolitis (NEC) is a devastating intestinal disease primarily
affecting preterm infants. The underlying mechanisms are poorly understood: mother's own …
affecting preterm infants. The underlying mechanisms are poorly understood: mother's own …
Clinical implications of preterm infant gut microbiome development
Perturbations to the infant gut microbiome during the first weeks to months of life affect
growth, development and health. In particular, assembly of an altered intestinal microbiota …
growth, development and health. In particular, assembly of an altered intestinal microbiota …
Maternal IgA protects against the development of necrotizing enterocolitis in preterm infants
Neonates are protected from colonizing bacteria by antibodies secreted into maternal milk.
Necrotizing enterocolitis (NEC) is a disease of neonatal preterm infants with high morbidity …
Necrotizing enterocolitis (NEC) is a disease of neonatal preterm infants with high morbidity …
BiG-SLiCE: A highly scalable tool maps the diversity of 1.2 million biosynthetic gene clusters
Background Genome mining for biosynthetic gene clusters (BGCs) has become an integral
part of natural product discovery. The> 200,000 microbial genomes now publicly available …
part of natural product discovery. The> 200,000 microbial genomes now publicly available …
Fecal filtrate transplantation protects against necrotizing enterocolitis
Necrotizing enterocolitis (NEC) is a life-threatening gastrointestinal disorder afflicting
preterm infants, which is currently unpreventable. Fecal microbiota transplantation (FMT) is a …
preterm infants, which is currently unpreventable. Fecal microbiota transplantation (FMT) is a …
[HTML][HTML] Ultra-deep sequencing of Hadza hunter-gatherers recovers vanishing gut microbes
The gut microbiome modulates immune and metabolic health. Human microbiome data are
biased toward industrialized populations, limiting our understanding of non-industrialized …
biased toward industrialized populations, limiting our understanding of non-industrialized …
Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants
S Sharif, N Meader, SJ Oddie… - Cochrane Database …, 2020 - cochranelibrary.com
Background Intestinal dysbiosis may contribute to the pathogenesis of necrotising
enterocolitis (NEC) in very preterm or very low birth weight infants. Dietary supplementation …
enterocolitis (NEC) in very preterm or very low birth weight infants. Dietary supplementation …