Psychedelics and other psychoplastogens for treating mental illness

MV Vargas, R Meyer, AA Avanes, M Rus… - Frontiers in …, 2021 - frontiersin.org
Psychedelics have inspired new hope for treating brain disorders, as they seem to be unlike
any treatments currently available. Not only do they produce sustained therapeutic effects …

Brain-derived neurotrophic factor in mood disorders and antidepressant treatments

E Castrén, M Kojima - Neurobiology of disease, 2017 - Elsevier
Levels of brain-derived neurotrophic factor (BDNF) are reduced in the brain and serum of
depressed patients and at least the reduction in serum levels is reversible upon successful …

Brain-derived neurotrophic factor and neuropsychiatric disorders

AE Autry, LM Monteggia - Pharmacological reviews, 2012 - Elsevier
Brain derived neurotrophic factor (BDNF) is the most prevalent growth factor in the central
nervous system (CNS). It is essential for the development of the CNS and for neuronal …

Sex differences in antidepressant efficacy

TA LeGates, MD Kvarta, SM Thompson - Neuropsychopharmacology, 2019 - nature.com
Sex differences have been observed across many psychiatric diseases, especially mood
disorders. For major depression, the most prevalent psychiatric disorder, females show a …

Cannabidiol induces rapid and sustained antidepressant-like effects through increased BDNF signaling and synaptogenesis in the prefrontal cortex

AJ Sales, MV Fogaça, AG Sartim, VS Pereira… - Molecular …, 2019 - Springer
Currently available antidepressants have a substantial time lag to induce therapeutic
response and a relatively low efficacy. The development of drugs that addresses these …

The role of BDNF and its receptors in depression and antidepressant drug action: reactivation of developmental plasticity

E Castrén, T Rantamäki - Developmental neurobiology, 2010 - Wiley Online Library
Recent evidence suggests that neuronal plasticity plays an important role in the recovery
from depression. Antidepressant drugs and electroconvulsive shock treatment increase the …

[HTML][HTML] Therapeutic potential of Hericium erinaceus for depressive disorder

PS Chong, ML Fung, KH Wong, LW Lim - International journal of …, 2020 - mdpi.com
Depression is a common and severe neuropsychiatric disorder that is one of the leading
causes of global disease burden. Although various anti-depressants are currently available …

Interaction between BDNF and serotonin: role in mood disorders

K Martinowich, B Lu - Neuropsychopharmacology, 2008 - nature.com
Brain-derived neurotrophic factor (BDNF) and serotonin (5-hydroxytryptamine, 5-HT) are two
seemingly distinct signaling systems that play regulatory roles in many neuronal functions …

The antidepressant fluoxetine restores plasticity in the adult visual cortex

JFM Vetencourt, A Sale, A Viegi, L Baroncelli… - Science, 2008 - science.org
We investigated whether fluoxetine, a widely prescribed medication for treatment of
depression, restores neuronal plasticity in the adult visual system of the rat. We found that …

Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate …

M Sairanen, G Lucas, P Ernfors, M Castrén… - Journal of …, 2005 - jneurosci.org
Antidepressants increase proliferation of neuronal progenitor cells and expression of brain-
derived neurotrophic factor (BDNF) in the hippocampus. We investigated the role of BDNF …