Research progress on the synthesis and pharmacology of 1, 3, 4-oxadiazole and 1, 2, 4-oxadiazole derivatives: a mini review
JJ Wang, W Sun, WD Jia, M Bian… - Journal of Enzyme …, 2022 - Taylor & Francis
Oxadiazole is a five-membered heterocyclic compound containing two nitrogen atoms and
one oxygen atom. The 1, 3, 4-oxadiazole and 1, 2, 4-oxadiazole have favourable physical …
one oxygen atom. The 1, 3, 4-oxadiazole and 1, 2, 4-oxadiazole have favourable physical …
Oxadiazole: A highly versatile scaffold in drug discovery
N Desai, J Monapara, A Jethawa… - Archiv der …, 2022 - Wiley Online Library
As a pharmacologically important heterocycle, oxadiazole paved the way to combat the
problem associated with the confluence of many commercially available drugs with different …
problem associated with the confluence of many commercially available drugs with different …
An understanding of mechanism-based approaches for 1, 3, 4-oxadiazole scaffolds as cytotoxic agents and enzyme inhibitors
The world's health system is plagued by cancer and a worldwide effort is underway to find
new drugs to treat cancer. There has been a significant improvement in understanding the …
new drugs to treat cancer. There has been a significant improvement in understanding the …
Current advances in the clinical development of anti-tubercular agents
Tuberculosis (TB) is a communicable airborne infectious disease caused by the
Mycobacterium tuberculosis (MTB) that primarily affects the lungs, and can disseminate to …
Mycobacterium tuberculosis (MTB) that primarily affects the lungs, and can disseminate to …
Synthesis, anticancer, antimicrobial and antioxidant potential of novel 4-(substituted phenyl-1, 3, 4-oxadiazol/thiadiazol-2-yl)-4-(4-substituted phenyl) azetidin-2-one …
By exploiting the ample biological potential of 1, 3, 4-oxadiazole/thiadiazole ring, 4-
substitutedphenyl-1, 3, 4-oxadiazol/Thiadiazol-2-yl)-4-(4-substitutedphenyl) azetidin-2-one …
substitutedphenyl-1, 3, 4-oxadiazol/Thiadiazol-2-yl)-4-(4-substitutedphenyl) azetidin-2-one …
Conventional and microwave‐assisted organic synthesis of novel antimycobacterial agents bearing furan and pyridine hybrids
Drug resistance in tuberculosis poses a serious threat to humanity because currently
available antitubercular drugs are ineffective against Mycobacterium tuberculosis (M …
available antitubercular drugs are ineffective against Mycobacterium tuberculosis (M …
Eco‐friendly approaches to 1, 3, 4‐oxadiazole derivatives: A comprehensive review of green synthetic strategies
This review article offers an environmentally benign synthesis of 1, 3, 4‐oxadiazole
derivatives, with a focus on sustainable methodologies that have minimal impact on the …
derivatives, with a focus on sustainable methodologies that have minimal impact on the …
Synthesis, characterization, and anti‐inflammatory properties of novel ethyl 3‐benzoyl‐7‐(trifluoromethyl) indolizine‐1‐carboxylate derivatives: In silico and in vitro …
HR Singh, P Kushwaha, R Tandon… - Chemical Biology & …, 2024 - Wiley Online Library
Abstract Series of 7‐(Trifluoromethyl) substituted indolizine 4a‐g was synthesized using the
one‐pot method. Spectroscopic techniques such as IR, 1H‐NMR, 13C‐NMR, and HRMS …
one‐pot method. Spectroscopic techniques such as IR, 1H‐NMR, 13C‐NMR, and HRMS …
Substrate‐based synthetic strategies and biological activities of 1, 3, 4‐oxadiazole: A review
Abstract The five‐membered 1, 3, 4‐oxadiazole heterocyclic ring has received considerable
attention because of its unique bio‐isosteric properties and an unusually wide spectrum of …
attention because of its unique bio‐isosteric properties and an unusually wide spectrum of …
Recent updates on synthesis, biological activity, and structure-activity relationship of 1, 3, 4-oxadiazole-quinoline hybrids: a review
Due to their diverse applications in industrial and synthetic organic chemistry, quinoline and
1, 3, 4-oxadiazole have become important heterocyclic compounds. Quinoline and 1, 3, 4 …
1, 3, 4-oxadiazole have become important heterocyclic compounds. Quinoline and 1, 3, 4 …