The successful isolation and characterization of an N-heterocyclic carbene in 1991 opened
up a new class of organic compounds for investigation. From these beginnings as academic …

Copper (I)-catalyzed 1, 3-dipolar cycloaddition between organic azides and terminal
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …

In this contribution, we provide a comprehensive overview of C–H activation methods
promoted by NHC–transition metal complexes, covering the literature since 2002 (the year …

The employment of N-heterocyclic carbenes (NHCs) to design luminescent metal
compounds has been the focus of recent intense investigations because of the strong σ …

Abstract Discovered in 2005, cyclic (alkyl)(amino) carbenes (CAACs) are among the most
nucleophilic (σ donating) and also electrophilic (π‐accepting) stable carbenes known to …

Heterogeneous catalysts represent the backbone of many industrial processes and thus
have a considerable societal impact. The active sites of these heterogeneous catalysts are …

Method B 692 3.7. Selective Trifluoromethylation of Multi-Functional Substrates 693 3.8.
Enantioselective Trifluoromethylation 695 3.8. 1. Aldehydes and Ketones: With Cinchona …

Conspectus Carbenes are compounds that feature a divalent carbon atom with only six
electrons in its valence shell. In the singlet state, they possess a lone pair of electrons and a …

Mesoionic carbenes are a subclass of the family of N-heterocyclic carbenes that generally
feature less heteroatom stabilization of the carbenic carbon and hence impart specific donor …

Since the latter quarter of the twentieth century, main group chemistry has undergone
significant advances. Power's timely review in 2010 highlighted the inherent differences …