The ability of cells to deal with different types of stressful situations in a precise and
coordinated manner is key for survival and involves various signalling networks. Over the …

Obesity is a complex, chronic disease and global public health challenge. Characterized by
excessive fat accumulation in the body, obesity sharply increases the risk of several …

Mammalian adipose tissue can be divided into two major types, namely, white adipose
tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function …

Development of obesity is primarily the result of imbalance between energy intake and
energy expenditure. Thyroid hormones influence energy expenditure by regulating cellular …

The p38 mitogen-activated kinase (MAPK) family controls cell adaptation to stress stimuli.
p38 function has been studied in depth in relation to cardiac development and function. The …

Obesity leads to multiple health problems, including diabetes, fatty liver, and even cancer.
Here, we report that urolithin A (UA), a gut-microflora–derived metabolite of pomegranate …

Obesity, an excess accumulation of white adipose tissue (WAT), has become a global
epidemic and is associated with complex diseases, such as type 2 diabetes and …

Adipose thermogenesis is repressed in obesity, reducing the homeostatic capacity to
compensate for chronic overnutrition. Inflammation inhibits adipose thermogenesis, but little …

Obesity is a health condition that has reached pandemic levels and is implicated in the
development and progression of type 2 diabetes mellitus, cancer and heart failure. A key …

Long-chain noncoding RNAs (lncRNAs) are RNAs that do not code for proteins, widely
present in eukaryotes. They regulate gene expression at multiple levels through different …