From antibacterial to antitumour agents: a brief review on the chemical and medicinal aspects of sulfonamides

H Azevedo-Barbosa, DF Dias, LL Franco… - Mini Reviews in …, 2020 - ingentaconnect.com
Sulfonamides have been in clinical use for many years, and the development of bioactive
substances containing the sulfonamide subunit has grown steadily in view of their important …

Dithiol proteins as guardians of the intracellular redox milieu in parasites: old and new drug targets in trypanosomes and malaria‐causing plasmodia

RL Krauth‐Siegel, H Bauer… - Angewandte Chemie …, 2005 - Wiley Online Library
Parasitic diseases such as slee** sickness, Chagas' heart disease, and malaria are major
health problems in poverty‐stricken areas. Antiparasitic drugs that are not only active but …

Quantum computational, spectroscopic investigations on N-(2-((2-chloro-4, 5-dicyanophenyl) amino) ethyl)-4-methylbenzenesulfonamide by DFT/TD-DFT with …

N Dege, H Gökce, OE Doğan, G Alpaslan… - Colloids and Surfaces A …, 2022 - Elsevier
The experimental (x-ray, FT-IR NMR and UV-Vis. Spectral data) and theoretical researches
of N-(2-((2-chloro-4, 5-dicyanophenyl) amino) ethyl)-4-methylbenzenesulfonamide molecule …

[LIVRE][B] Side reactions in Organic Synthesis: a guide to successful synthesis design

FZ Dörwald - 2006 - books.google.com
Most syntheses in the chemical research laboratory fail and usually require several attempts
before proceeding satisfactorily. Failed syntheses are not only discouraging and frustrating …

“Recycling” classical drugs for malaria

C Teixeira, N Vale, B Perez, A Gomes… - Chemical …, 2014 - ACS Publications
Malaria has been a human health concern ever since the dawn of mankind, but despite the
huge struggles made to date to fight this infection, in 2012 over half a million people were …

Antibacterial metal complexes of o‐sulfamoylbenzoic acid: Synthesis, characterization, and DFT study

WA Siddiqui, M Khalid, A Ashraf, I Shafiq… - Applied …, 2022 - Wiley Online Library
Herein, antibacterial transition metal complexes of ML2 type having o‐sulfamoylbenzoic
acid as ligand were synthesized from saccharin. All characterization techniques confirmed …

[PDF][PDF] Biological activity and synthesis of sulfonamide derivatives: a brief review

A Kołaczek, I Fusiarz, J Ławecka, D Branowska - Chemik, 2014 - researchgate.net
Sulfonamides (sulfa drugs) were the first drugs largely employed and systematically used as
preventive and chemotherapeutic agents against various diseases [1]. Over 30 drugs …

Design, synthesis, ADME prediction and pharmacological evaluation of novel benzimidazole-1, 2, 3-triazole-sulfonamide hybrids as antimicrobial and antiproliferative …

FF Al-Blewi, MA Almehmadi, MR Aouad… - Chemistry Central …, 2018 - Springer
Background Nitrogen heterocyclic rings and sulfonamides have attracted attention of several
researchers. Results A series of regioselective imidazole-based mono-and bis-1, 4 …

Biological evaluation of some new N-(2, 6-dimethoxypyrimidinyl) thioureido benzenesulfonamide derivatives as potential antimicrobial and anticancer agents

MM Ghorab, MS Alsaid, MSA El-Gaby… - European Journal of …, 2016 - Elsevier
A series of novel heterocyclic thioureas 3a-u containing sulfonamide moiety have been
synthesized by the condensation of isothiocyanatobenzenesulfonamide 2 with a variety of …

Synthesis of Benzimidazole‐Sulfonyl Derivatives and Their Biological Activities

E Mulugeta, Y Samuel - Biochemistry Research International, 2022 - Wiley Online Library
Currently, the synthesis of new compounds with potential bioactivities has become a central
issue in the drug discovery arena. Among these new compounds, benzimidazole‐sulfonyl …