Emerging and reemerging neglected tropical diseases: a review of key characteristics, risk factors, and the policy and innovation environment

TK Mackey, BA Liang, R Cuomo, R Hafen… - Clinical microbiology …, 2014 - Am Soc Microbiol
In global health, critical challenges have arisen from infectious diseases, including the
emergence and reemergence of old and new infectious diseases. Emergence and …

[HTML][HTML] Chagas disease in the 21st century: a public health success or an emerging threat?

KM Bonney - Parasite, 2014 - ncbi.nlm.nih.gov
Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is a major public
health burden in Latin America and a potentially serious emerging threat to a number of …

Chagas Disease Ecology in the United States: Recent Advances in Understanding Trypanosoma cruzi Transmission Among Triatomines, Wildlife, and Domestic …

RE Busselman, SA Hamer - Annual review of animal …, 2022 - annualreviews.org
Chagas disease, a neglected tropical disease present in the Americas, is caused by the
parasite Trypanosoma cruzi and is transmitted by triatomine kissing bug vectors. Hundreds …

[HTML][HTML] Immunity and vaccine development efforts against Trypanosoma cruzi

LE Rios, JC Vázquez-Chagoyán, AO Pacheco… - Acta tropica, 2019 - Elsevier
Trypanosoma cruzi (T. cruzi) is the causative agent for Chagas disease (CD). There is a
critical lack of methods for prevention of infection or treatment of acute infection and chronic …

CD8+ T cells in Trypanosoma cruzi infection

RL Tarleton - Seminars in immunopathology, 2015 - Springer
Trypanosoma cruzi infection and Chagas disease remains among the most neglected of the
neglected tropical diseases. Despite this, studies of the immune response to T. cruzi have …

New vaccines for neglected parasitic diseases and dengue

CM Beaumier, PM Gillespie, PJ Hotez… - Translational Research, 2013 - Elsevier
Neglected tropical diseases (NTDs) are a significant source of morbidity and socioeconomic
burden among the world's poor. Virtually all of the 2.4 billion people who live on less than $2 …

Accelerating the development of a therapeutic vaccine for human Chagas disease: rationale and prospects

E Dumonteil, ME Bottazzi, B Zhan… - Expert review of …, 2012 - Taylor & Francis
Chagas disease is a leading cause of heart disease affecting approximately 10 million
people in Latin America and elsewhere worldwide. The two major drugs available for the …

A prophylactic α-Gal-based glycovaccine effectively protects against murine acute Chagas disease

S Portillo, BG Zepeda, E Iniguez, JJ Olivas, NH Karimi… - npj Vaccines, 2019 - nature.com
Chagas disease (ChD), caused by the hemoflagellate parasite Trypanosoma cruzi, affects
six to seven million people in Latin America. Lately, it has become an emerging public …

Chagas disease: a silent threat for dogs and humans

J Durães-Oliveira, J Palma-Marques, C Moreno… - International Journal of …, 2024 - mdpi.com
Chagas disease (CD) is a vector-borne Neglected Zoonotic Disease (NZD) caused by a
flagellate protozoan, Trypanosoma cruzi, that affects various mammalian species across …

Nanotechnology-based strategies in parasitic disease management: from prevention to diagnosis and treatment

R Tiwari, RP Gupta, VK Singh, A Kumar, Rajneesh… - ACS …, 2023 - ACS Publications
Parasitic infections are a major global health issue causing significant mortality and
morbidity. Despite substantial advances in the diagnostics and treatment of these diseases …