Zinc is an important trace element in biology. An important pool of zinc in the brain is the one
present in synaptic vesicles in a subgroup of glutamatergic neurons. In this form it can be …

Abstract Zinc transporter 3 (ZnT3) is the sole mechanism responsible for concentrating zinc
ions within synaptic vesicles in a subset of the brain's glutamatergic neurons. This vesicular …

Hippocampal CA1 pyramidal neurons have frequently been regarded as a homogeneous
cell population in biophysical, pharmacological and modeling studies. We found robust …

Many central neurons possess large acid-activated currents, yet their molecular identity is
unknown. We found that eliminating the acid sensing ion channel (ASIC) abolished H+ …

The murine ZnT3 gene was cloned by virtue of its homology to the ZnT2 gene, which
encodes a membrane protein that facilitates sequestration of zinc in endosomal vesicles …

Two new fluorescent sensors for Zn2+ that utilize fluorescein as a reporting group, Zinpyr-1
and Zinpyr-2, have been synthesized and characterized. Zinpyr-1 is prepared in one step via …

The mammalian protein ZnT3 resides on synaptic vesicle membranes of zinc-containing
neurons, suggesting its possible role in vesicular zinc transport. We show here that …

Zinc transporter-3 (ZnT-3), a member of a growing family of mammalian zinc transporters, is
expressed in regions of the brain that are rich in histochemically reactive zinc (as revealed …

Zinc is a life‐sustaining trace element, serving structural, catalytic, and regulatory roles in
cellular biology. It is required for normal mammalian brain development and physiology …

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