Molecular basis of a high Hb A2/Hb Fβ-thalassemia trait: a retrospective analysis, genotype-phenotype interaction, diagnostic implication, and identification of a novel …

C Soontornpanawet, K Singha, H Srivorakun… - PeerJ, 2023‏ - peerj.com
Background β 0-thalassemia deletion removing 5 β-globin promoter usually presents
phenotype with high hemoglobin (Hb) A 2 and Hb F levels. We report the molecular …

First Report of Filipino β0-Thalassemia/β-Thalassemia in a Chinese Family

M Chen, A Lv, S Zhang, J Zheng, M Zhang, L Chen… - …, 2024‏ - Taylor & Francis
A pregnant woman living in Fujian Province, southeastern China, presented due to a risk of
having a baby with β-thalassemia major, during her second pregnancy, since she and her …

Genotype-phenotype study of β-thalassemia patients in Sabah

L Suali, FA Mohammad Salih, MY Ibrahim… - …, 2022‏ - Taylor & Francis
Abstract β-thalassemia is a serious public health problem in Sabah due to its high
prevalence. This study aimed to investigate the effects of different types of β-globin gene …

The Effect of Single Nucleotide Polymorphisms on Clinical Phenotypes of Sabahan Transfusion-Dependent β-Thalassemia Patients with Homozygous Filipino β0 …

L Suali, FA Mohammad Salih, MY Ibrahim… - …, 2025‏ - Taylor & Francis
Sabah has the highest prevalence of β-thalassemia in Malaysia, with the Filipino β0-deletion
as the predominant mutation. Patients with the homozygous Filipino β0-deletion exhibit …

[PDF][PDF] Demographic and Socioeconomic Profile of Transfusion Dependent Beta-Thalassemia Major Patients in Sabah.

JG Chin, IJA Hamid, K Gunasagaran… - Malaysian Journal of …, 2019‏ - medic.upm.edu.my
ABSTRACT Introduction: Thalassemia prevalence in Malaysia is highest in Sabah. This
study was conducted to characterize the demographic and socioeconomic profile of …

Prevalence of RDB, RSa, Hinc and Xmn polymorphisms and HBBS11D haplotypes in patients with thalassemia minor

SS Irankhah, S Hoseini-Asl, M Valizadeh… - Cellular, Molecular …, 2022‏ - cmbr-journal.com
Background: Beta-thalassemia is one of the most common genetic diseases with autosomal
recessive inherited patterns in the world and is one of the most common diseases in Iran that …

[PDF][PDF] To Study the β-Globin Haplotype Pattern of Descent of a Set of Linked Alleles Occurring on the Same Chromosome in the Northern Province of India

N Nigam, S Sinha, N Verma, H Gupta, G Fatima… - Cureus, 2023‏ - cureus.com
Objective: To study the five mutations commonly prevalent in North India, ie, IVS-I-5 (G→ C),
619 bp deletion, IVS-I-1 (G→ T), codon 41/42 (-TTCT), and codon 8/9 (+ G), in the beta …

MOTHERS WITH MULTIPLE β-THALASSEMIA MAJOR CHILDREN IN SABAH, MALAYSIA: A QUALITATIVE STUDY EXPLORING THE CONTRIBUTING FACTORS …

JG Chin, IJ Abd Hamid, J Amir… - Journal of Health and …, 2022‏ - fiqh.um.edu.my
Despite having the highest prevalence of thalassemia in Malaysia, studies exploring factors
that contribute to high thalassemia births in Sabah is still lacking. This study aimed to …

[CITATION][C] MOTHERS WITH MULTIPLE β-THALASSEMIA MAJOR CHILDREN IN SABAH, MALAYSIA: A QUALITATIVE STUDY EXPLORING THE CONTRIBUTING …