25th anniversary article: Rational design and applications of hydrogels in regenerative medicine

N Annabi, A Tamayol, JA Uquillas, M Akbari… - Advanced …, 2014 - Wiley Online Library
Hydrogels are hydrophilic polymer‐based materials with high water content and physical
characteristics that resemble the native extracellular matrix. Because of their remarkable …

What does plant-based vaccine technology offer to the fight against COVID-19?

S Rosales-Mendoza, VA Márquez-Escobar… - Vaccines, 2020 - mdpi.com
The emergence of new pathogenic viral strains is a constant threat to global health, with the
new coronavirus strain COVID-19 as the latest example. COVID-19, caused by the SARS …

Development of systems for the production of plant-derived biopharmaceuticals

KB Moon, JS Park, YI Park, IJ Song, HJ Lee, HS Cho… - Plants, 2019 - mdpi.com
Over the last several decades, plants have been developed as a platform for the production
of useful recombinant proteins due to a number of advantages, including rapid production …

Elastin-like polypeptides: Therapeutic applications for an emerging class of nanomedicines

J Despanie, JP Dhandhukia, SF Hamm-Alvarez… - Journal of Controlled …, 2016 - Elsevier
Elastin-like polypeptides (ELPs) constitute a genetically engineered class of 'protein
polymers' derived from human tropoelastin. They exhibit a reversible phase separation …

Plant‐made oral vaccines against human infectious diseases—are we there yet?

HT Chan, H Daniell - Plant biotechnology journal, 2015 - Wiley Online Library
Although the plant‐made vaccine field started three decades ago with the promise of
develo** low‐cost vaccines to prevent infectious disease outbreaks and epidemics …

Elastin‐like polypeptides: A strategic fusion partner for biologics

A Yeboah, RI Cohen, C Rabolli… - Biotechnology and …, 2016 - Wiley Online Library
Elastin‐like peptides (ELPs) are derivatives of tropoelastin with a unique property that allows
them to stay soluble below a certain critical temperature but reversibly form aggregates …

Elastomeric recombinant protein-based biomaterials

N Annabi, SM Mithieux, G Camci-Unal… - Biochemical …, 2013 - Elsevier
Elastomeric protein-based biomaterials, produced from elastin derivatives, are widely
investigated as promising tissue engineering scaffolds due to their remarkable properties …

Contributions of the international plant science community to the fight against infectious diseases in humans—part 2: Affordable drugs in edible plants for endemic and …

W He, C Baysal, M Lobato Gomez… - Plant biotechnology …, 2021 - Wiley Online Library
The fight against infectious diseases often focuses on epidemics and pandemics, which
demand urgent resources and command attention from the health authorities and media …

Biotechnological applications of elastin-like polypeptides and the inverse transition cycle in the pharmaceutical industry

EE Fletcher, D Yan, AA Kosiba, Y Zhou, H Shi - Protein expression and …, 2019 - Elsevier
Proteins are essential throughout the biological and biomedical sciences and the
purification strategies of proteins of interest have advanced over centuries. Elastin-like …

ELPylated anti‐human TNF therapeutic single‐domain antibodies for prevention of lethal septic shock

U Conrad, I Plagmann, S Malchow… - Plant biotechnology …, 2011 - Wiley Online Library
Tumour necrosis factor (TNF) is a major pro‐inflammatory cytokine involved in multiple
inflammatory diseases. The detrimental activity of TNF can be blocked by various …