Non-alcoholic fatty liver disease (NAFLD) includes a range of hepatic manifestations,
starting with liver steatosis and potentially evolving towards non-alcoholic steatohepatitis …

The liver is the sixth most common site of primary cancer in humans, and generally arises in
a background of cirrhosis and inflammation. Moreover, the liver is frequently colonized by …

Dissecting and understanding the cancer ecosystem, especially that around the tumor
margins, which have strong implications for tumor cell infiltration and invasion, are essential …

Exposure of cells to high voltage electric pulses increases transiently membrane
permeability through membrane electroporation. Electroporation can be reversible and is …

Hepatocellular cell death and macrophage proinflammatory activation contribute to the
pathology of various liver diseases, during which XBP1 plays an important role. However …

The liver is a highly dynamic metabolic organ that plays critical roles in plasma protein
synthesis, gluconeogenesis and glycogen storage, cholesterol metabolism and bile acid …

Liver regeneration is a complex process involving the crosstalk of multiple cell types,
including hepatocytes, hepatic stellate cells, endothelial cells and inflammatory cells. The …

Alcoholic liver disease (ALD) is a globally prevalent chronic liver disease caused by chronic
or binge consumption of alcohol. The liver is the major organ that metabolizes alcohol; …

Caspases are an evolutionary conserved family of cysteine proteases that are centrally
involved in cell death and inflammation responses. A wealth of foundational insight into the …

Inflammation is a biological response of the immune system that can be triggered by a
variety of factors, including pathogens, damaged cells and toxic compounds. These factors …