Ageing and chronic degenerative pathologies demonstrate the shared characteristics of
high bioavailability of reactive oxygen species (ROS) and oxidative stress, chronic/persistent …

Diabetes represents a major public health concern with a considerable impact on human life
and healthcare expenditures. It is now well established that diabetes is characterized by a …

The advent of mesenchymal stem cell (MSC)-based therapies for clinical therapeutics has
been an exciting and new innovation for the treatment of a variety of diseases associated …

Mesenchymal stem cells (MSCs), an ideal cell source for regenerative therapy with no
ethical issues, play an important role in diabetic foot ulcer (DFU). Growing evidence has …

Among the various types of cell-to-cell signaling, paracrine signaling comprises those
signals that are transmitted over short distances between different cell types. In the human …

Mesenchymal stem cells (MSCs) are multipotent, self-renewing cells that can be found in
almost all postnatal organs and tissues. The main functional characteristics of MSCs are …

Osteoporosis, a global age-related health problem in both male and female elderly,
insidiously deteriorates the microstructure of bone, particularly at trabecular sites, such as …

Objective—Cardiac damage and vascular dysfunction are major causes of morbidity and
mortality in hypertension. In the present study, we explored the beneficial therapeutic effect …

Mesenchymal stem/stromal cells (MSCs) are becoming increasingly important for the
development of cell therapeutics in regenerative medicine. Featuring immunomodulatory …

Background We recently reported that ER stress plays a key role in vascular endothelial
dysfunction during hypertension. In this study we aimed to elucidate the mechanisms by …