MalaCards: an amalgamated human disease compendium with diverse clinical and genetic annotation and structured search
N Rappaport, M Twik, I Plaschkes, R Nudel… - Nucleic acids …, 2017 - academic.oup.com
The MalaCards human disease database (http://www. malacards. org/) is an integrated
compendium of annotated diseases mined from 68 data sources. MalaCards has a web card …
compendium of annotated diseases mined from 68 data sources. MalaCards has a web card …
The genecards suite
The GeneCards® database of human genes was launched in 1997 and has expanded
since then to encompass gene-centric, disease-centric, and pathway-centric entities and …
since then to encompass gene-centric, disease-centric, and pathway-centric entities and …
GeneHancer: genome-wide integration of enhancers and target genes in GeneCards
A major challenge in understanding gene regulation is the unequivocal identification of
enhancer elements and uncovering their connections to genes. We present GeneHancer, a …
enhancer elements and uncovering their connections to genes. We present GeneHancer, a …
The GeneCards suite: from gene data mining to disease genome sequence analyses
G Stelzer, N Rosen, I Plaschkes… - Current protocols in …, 2016 - Wiley Online Library
GeneCards, the human gene compendium, enables researchers to effectively navigate and
inter‐relate the wide universe of human genes, diseases, variants, proteins, cells, and …
inter‐relate the wide universe of human genes, diseases, variants, proteins, cells, and …
In Silico Toxicology Data Resources to Support Read-Across and (Q)SAR
G Pawar, JC Madden, D Ebbrell, JW Firman… - Frontiers in …, 2019 - frontiersin.org
A plethora of databases exist online that can assist in in silico chemical or drug safety
assessment. However, a systematic review and grou** of databases, based on purpose …
assessment. However, a systematic review and grou** of databases, based on purpose …
Genome-wide analysis of somatic noncoding mutation patterns in cancer
We established a genome-wide compendium of somatic mutation events in 3949 whole
cancer genomes representing 19 tumor types. Protein-coding events captured well …
cancer genomes representing 19 tumor types. Protein-coding events captured well …
Xenbase: a genomic, epigenomic and transcriptomic model organism database
Abstract Xenbase (www. xenbase. org) is an online resource for researchers utilizing
Xenopus laevis and Xenopus tropicalis, and for biomedical scientists seeking access to data …
Xenopus laevis and Xenopus tropicalis, and for biomedical scientists seeking access to data …
GeneAnalytics: an integrative gene set analysis tool for next generation sequencing, RNAseq and microarray data
Postgenomics data are produced in large volumes by life sciences and clinical applications
of novel omics diagnostics and therapeutics for precision medicine. To move from “data-to …
of novel omics diagnostics and therapeutics for precision medicine. To move from “data-to …
VarElect: the phenotype-based variation prioritizer of the GeneCards Suite
Background Next generation sequencing (NGS) provides a key technology for deciphering
the genetic underpinnings of human diseases. Typical NGS analyses of a patient depict tens …
the genetic underpinnings of human diseases. Typical NGS analyses of a patient depict tens …
Mouse aging cell atlas analysis reveals global and cell type-specific aging signatures
Aging is associated with complex molecular and cellular processes that are poorly
understood. Here we leveraged the Tabula Muris Senis single-cell RNA-seq data set to …
understood. Here we leveraged the Tabula Muris Senis single-cell RNA-seq data set to …