Apicomplexan parasites are a group of eukaryotic protozoans with diverse biology that have
affected human health like no other group of parasites. These obligate intracellular parasites …

The phylum Apicomplexa has been defined by the presence of the apical complex, a
structure composed of secretory organelles and specific cytoskeletal elements. A …

The cilium-centrosome complex contains triplet, doublet, and singlet microtubules. The
lumenal surfaces of each microtubule within this diverse array are decorated by microtubule …

The apical complex is the instrument of invasion used by apicomplexan parasites, and the
conoid is a conspicuous feature of this apparatus found throughout this phylum. The conoid …

The inner membrane complex (IMC) of Toxoplasma gondii is a peripheral membrane system
that is composed of flattened alveolar sacs that underlie the plasma membrane, coupled to a …

In living cells, microtubules (MTs) play pleiotropic roles, which require very different
mechanical properties. Unlike the dynamic MTs found in the cytoplasm of metazoan cells …

The apical complex is the definitive cell structure of phylum Apicomplexa, and is the focus of
the events of host cell penetration and the establishment of intracellular parasitism. Despite …

In Apicomplexa, rhoptry discharge is essential for invasion and involves an apical vesicle
(AV) docking one or two rhoptries to a macromolecular secretory apparatus. Toxoplasma …

The body plan of the human parasite Toxoplasma gondii has a well-defined polarity. The
minus ends of the 22 cortical microtubules are anchored to the apical polar ring, which is a …

Members of the family of calcium dependent protein kinases (CDPK's) are abundant in
certain pathogenic parasites and absent in mammalian cells making them strong drug target …