[HTML][HTML] Neutrophil extracellular traps promote M1 macrophage polarization in gouty inflammation via targeting hexokinase-2
H Tan, S Zhang, Z Zhang, J Zhang, Z Wang… - Free Radical Biology …, 2024 - Elsevier
Abstract Peptidylarginine deiminase 4 (PAD4)-dependent neutrophil extracellular trap (NET)
formation is a new neutrophil death mechanism. Increased NET formation has been …
formation is a new neutrophil death mechanism. Increased NET formation has been …
Development and characterization of liposomal formulations containing sesquiterpene lactones for the treatment of chronic gout
R Cunha Matosinhos, F Frézard… - Scientific Reports, 2024 - nature.com
Gout and hyperuricemia are characterized by high uric acid levels, and their treatment
involves medications that have adverse effects. In this study, we evaluated oral liposomal …
involves medications that have adverse effects. In this study, we evaluated oral liposomal …
Investigating the involvement of the NLRP3/ASC/caspase-1 and NF-κb/MAPK pathways in the pathogenesis of gouty arthritis: Insights from irradiated and non …
HS Mohammed, HA Elariny, NA Seif-Eldein… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Trifolium alexandrinum L.(TA), has traditionally been used
in folk medicine for its anti-inflammatory properties against hyperuricemia and gout …
in folk medicine for its anti-inflammatory properties against hyperuricemia and gout …
[HTML][HTML] Causal effects of gut microbiota on gout and hyperuricemia: insights from genome-wide Mendelian randomization, RNA-sequencing, 16S rRNA sequencing …
X Liu, Z Feng, F Zhang, B Wang, Z Wei… - Bioscience …, 2024 - portlandpress.com
Background: This study investigated the causal relationship between gut microbiota (GM),
serum metabolome, and host transcriptome in the development of gout and hyperuricemia …
serum metabolome, and host transcriptome in the development of gout and hyperuricemia …