Olfactory receptors (ORs) form the most important chemosensory receptor family responsible
for our sense of smell in the nasal olfactory epithelium. This receptor family belongs to the …

Olfactory receptors (ORs) are widely expressed in extra-nasal tissues, where they participate
in the regulation of divergent physiological processes. An increasing body of evidence over …

Mammalian sense of smell is triggered by interaction between odorant molecules and a
class of proteins, called olfactory receptors (ORs). These receptors, expressed at the surface …

G protein-coupled receptors (GPCRs) conserve common structural folds and activation
mechanisms, yet their ligand spectra and functions are highly diverse. This work …

Sensory processing in olfactory systems is organized across olfactory bulb glomeruli,
wherein axons of peripheral sensory neurons expressing the same olfactory receptor co …

In numerous insects, the olfactory receptor family forms a unique class of heteromeric cation
channels. Recent progress in resolving the odorant receptor structures offers unprecedented …

Humans have 396 unique, intact olfactory receptors (ORs), G-protein coupled receptors
(GPCRs) containing receptor-specific binding sites; other mammals have more. Activation of …

The perception of odors relies on combinatorial codes consisting of odorant receptor (OR)
response patterns to encode odor identity. Modulation of these patterns by odorant …

Mammalian odorant receptors are a diverse and rapidly evolving set of G protein-coupled
receptors expressed in olfactory cilia membranes. Most odorant receptors show little to no …

With approximately 400 encoding genes in humans, odorant receptors (ORs) are the largest
subfamily of class AG protein-coupled receptors (GPCRs). Despite its high relevance and …