Molecular Characterization and Sterol Profiles Identify Nonsynonymous Mutations in ERG2 as a Major Mechanism Conferring Reduced Susceptibility to Amphotericin …

M Asadzadeh, W Alfouzan, JE Parker… - Microbiology …, 2023 - journals.asm.org
The molecular basis of reduced susceptibility to amphotericin B (rs-AMB) among any yeasts
is poorly defined. Genetic alterations in genes involved in ergosterol biosynthesis and total …

[HTML][HTML] Genotypic and Phenotypic Diversity of Kluyveromyces marxianus Isolates Obtained from the Elaboration Process of Two Traditional Mexican Alcoholic Beverages …

P Lappe-Oliveras, M Avitia, SD Sánchez-Robledo… - Journal of Fungi, 2023 - mdpi.com
Seven Kluyveromyces marxianus isolates from the elaboration process of pulque and
henequen mezcal were characterized. The isolates were identified based on the sequences …

Development of a Ribosome Profiling Protocol to Study Translation in the yeast Kluyveromyces marxianus

DA Fenton, SJ Kiniry, MM Yordanova, PV Baranov… - BioRxiv, 2022 - biorxiv.org
Kluyveromyces marxianus is an interesting and important yeast because of particular traits
like thermotolerance and rapid growth, and applications in food and industrial …

Dissecting an ancient stress resistance trait syndrome in the compost yeast Kluyveromyces marxianus

KE Christensen, A Duarte, Z Ma, JL Edwards… - …, 2023 - pmc.ncbi.nlm.nih.gov
In the search to understand how evolution builds new traits, ancient events are often the
hardest to dissect. Species-unique traits pose a particular challenge for geneticists—cases …

Integrated data-driven reannotation of the Kluyveromyces marxianus genome reveals an expanded protein coding repertoire

DA Fenton, M Świrski, PBF O'Connor, SJ Kiniry… - BioRxiv, 2022 - biorxiv.org
Many new biotechnology applications make use of non-traditional yeast species that
possess characteristics and traits that are advantageous in specific settings. To a large …

[HTML][HTML] Transcriptional and translational profiling in yeast reveals the use of diverse genome decoding mechanisms to generate functionally distinct proteoforms

DA Fenton, M Świrski, PBF O'Connor, SJ Kiniry… - 2022 - europepmc.org
The coding potential of the eukaryotic genome can be greatly expanded by the regulated
use of mechanisms that generate more than one protein product from a gene. We combined …

[PDF][PDF] Development of synthetic biology tools for Kluyveromyces

JA Akinola - 2023 - cora.ucc.ie
Aromatic molecules are highly sought after compounds because they are useful in various
aspects of life. Some are used as food additives and the bioactive nature of many makes …

[PDF][PDF] Adaptive Laboratory Evolution to enhance Kluyveromyces marxianus tolerance to sugar beet pulp hydrolysates

P Jayaprakash, F Martani, JP Morrissey… - Application of direct …, 2022 - cora.ucc.ie
The lack of tolerance of K. marxianus to inhibitory compounds, particularly weak organic
acids, produced during pretreatment, hinders its use when hydrolyzed LCB is used as …