Short-chain fatty acids in diseases

D Zhang, YP Jian, YN Zhang, Y Li, LT Gu… - Cell Communication and …, 2023 - Springer
Short-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation
of dietary fibre in the gastrointestinal tract. The absorption of SCFAs is mediated by substrate …

The gut microbiome in social anxiety disorder: evidence of altered composition and function

MI Butler, TFS Bastiaanssen, C Long-Smith… - Translational …, 2023 - nature.com
The microbiome-gut-brain axis plays a role in anxiety, the stress response and social
development, and is of growing interest in neuropsychiatric conditions. The gut microbiota …

Interplay of metabolome and gut microbiome in individuals with major depressive disorder vs control individuals

N Amin, J Liu, B Bonnechere… - JAMA …, 2023 - jamanetwork.com
Importance Metabolomics reflect the net effect of genetic and environmental influences and
thus provide a comprehensive approach to evaluating the pathogenesis of complex …

Genome–environment interactions and psychiatric disorders

J Peedicayil - Biomedicines, 2023 - mdpi.com
Environmental factors are known to interact with the genome by altering epigenetic
mechanisms regulating gene expression and contributing to the pathogenesis of psychiatric …

The gut microbiome is associated with brain structure and function in schizophrenia

S Li, J Song, P Ke, L Kong, B Lei, J Zhou, Y Huang… - Scientific reports, 2021 - nature.com
The effect of the gut microbiome on the central nervous system and its possible role in
mental disorders have received increasing attention. However, knowledge about the …

[HTML][HTML] Naringenin regulates gut microbiota and SIRT1/PGC-1ɑ signaling pathway in rats with letrozole-induced polycystic ovary syndrome

YX Wu, XY Yang, BS Han, YY Hu, T An, BH Lv… - Biomedicine & …, 2022 - Elsevier
Purpose To evaluate the effect of naringenin on improving PCOS and explore the
mechanism. Methods Firstly, we carried out differential gene expression analysis from …

Probiotic Bifidobacterium longum BB68S Improves Cognitive Functions in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Trial

S Shi, Q Zhang, Y Sang, S Ge, Q Wang, R Wang, J He - Nutrients, 2022 - mdpi.com
Probiotics could improve cognitive functions in patients with neurological disorders such as
Alzheimer's disease, but the effects on cognitive function in healthy older adults without …

Maternal weight, gut microbiota, and the association with early childhood behavior: the PREOBE follow-up study

A Nieto-Ruiz, T Cerdó, B Jordano… - Child and Adolescent …, 2023 - Springer
Background and aim Maternal overweight and breastfeeding seem to have a significant
impact on the gut microbiota colonization process, which co-occurs simultaneously with …

Gut microbiome and schizophrenia: insights from two-sample Mendelian randomization

K Zhou, A Baranova, H Cao, J Sun, F Zhang - Schizophrenia, 2024 - nature.com
Growing evidence suggests a potential link between the gut microbiome and schizophrenia.
However, it is unclear whether the gut microbiome is causally associated with …

Leveraging the microbiome to understand clinical heterogeneity in depression: findings from the T-RAD study

CR Chin Fatt, S Asbury, MK Jha, A Minhajuddin… - Translational …, 2023 - nature.com
Alterations in the gut microbiome have been linked to a variety of mental illnesses including
anxiety and depression. This study utilized advanced bioinformatics tools that integrated …