Membrane fusion is a key process in all living organisms that contributes to a variety of
biological processes including viral infection, cell fertilization, as well as intracellular …

Research for three decades and major recent advances have provided crucial insights into
how neurotransmitters are released by Ca2+‐triggered synaptic vesicle exocytosis, leading …

SNARE proteins and Sec1/Munc18 (SM) proteins constitute the core molecular engine that
drives nearly all intracellular membrane fusion and exocytosis. While SNAREs are known to …

Extensive research has yielded crucial insights into the mechanism of neurotransmitter
release, and working models for the functions of key proteins involved in release. The …

Intracellular membrane fusion is mediated in most cases by membrane-bridging complexes
of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) …

SNAREs are the core machinery mediating membrane fusion. In this review, we provide an
update on the recent progress on SNAREs regulating membrane fusion events, especially …

This review summarizes current knowledge of synaptic proteins that are central to synaptic
vesicle fusion in presynaptic active zones, including SNAREs (s oluble N-ethylmaleimide …

The synaptic vesicle (SV) protein synaptotagmin-1 (Syt1) is the Ca2+ sensor for fast
synchronous release. Biochemical and structural data suggest that Syt1 interacts with …

Magnetic force spectroscopy is a rapidly develo** single molecule technique that has
found numerous applications at the interface of physics and biology. Since the invention of …

Neuronal communication depends on exquisitely regulated membrane fusion between
synaptic vesicles and presynaptic neurons, which results in neurotransmitter release in …