Overview of oral cavity squamous cell carcinoma: Risk factors, mechanisms, and diagnostics
A Chamoli, AS Gosavi, UP Shirwadkar, KV Wangdale… - Oral oncology, 2021 - Elsevier
Oral cavity squamous cell carcinoma (OCSCC) is the most common malignancy of the oral
cavity. The substantial risk factors for OCSCC are the consumption of tobacco products …
cavity. The substantial risk factors for OCSCC are the consumption of tobacco products …
Antitumour immunity regulated by aberrant ERBB family signalling
S Kumagai, S Koyama, H Nishikawa - Nature Reviews Cancer, 2021 - nature.com
Aberrant signalling of ERBB family members plays an important role in tumorigenesis and in
the escape from antitumour immunity in multiple malignancies. Molecular-targeted agents …
the escape from antitumour immunity in multiple malignancies. Molecular-targeted agents …
Context-specific determinants of the immunosuppressive tumor microenvironment in pancreatic cancer
Immunotherapies have shown benefits across a range of human cancers, but not pancreatic
ductal adenocarcinoma (PDAC). Recent evidence suggests that the immunosuppressive …
ductal adenocarcinoma (PDAC). Recent evidence suggests that the immunosuppressive …
[HTML][HTML] Immune biomarkers of response to immune-checkpoint inhibitors in head and neck squamous cell carcinoma
Anti-programmed cell death protein 1 (PD-1) agents have become the standard of care for
platinum-refractory recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) …
platinum-refractory recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) …
Clinical-genomic determinants of immune checkpoint blockade response in head and neck squamous cell carcinoma
BACKGROUND Recurrent and/or metastatic (R/M) head and neck squamous cell carcinoma
(HNSCC) is generally an incurable disease, with patients experiencing median survival of …
(HNSCC) is generally an incurable disease, with patients experiencing median survival of …
Effects of tobacco smoking on the tumor immune microenvironment in head and neck squamous cell carcinoma
JV de la Iglesia, RJC Slebos, L Martin-Gomez… - Clinical Cancer …, 2020 - AACR
Purpose: Patients with head and neck squamous cell carcinoma (HNSCC) who actively
smoke during treatment have worse survival compared with never-smokers and former …
smoke during treatment have worse survival compared with never-smokers and former …
Radioimmunotherapy for the treatment of head and neck cancer
SD Karam, D Raben - The Lancet Oncology, 2019 - thelancet.com
Evidence to date shows that immune checkpoint inhibitors have little benefit in most patients
with head and neck squamous cell carcinoma (HNSCC). Intense interest is focused on …
with head and neck squamous cell carcinoma (HNSCC). Intense interest is focused on …
The confounders of cancer immunotherapy: roles of lifestyle, metabolic disorders and sociological factors
Simple Summary The human immune system is robustly equipped to keep unnatural cell
growth in check in the body to suppress cancer progression. However, the cells and …
growth in check in the body to suppress cancer progression. However, the cells and …
[HTML][HTML] Immune response against head and neck cancer: biological mechanisms and implication on therapy
F Perri, F Ionna, F Longo, GDV Scarpati… - Translational …, 2020 - Elsevier
Head and neck carcinoma (HNC) are diseases arising from several tracts of the
aerodigestive ways. Most HNC are squamous cell carcinoma (SCCHN). Immunotherapy is a …
aerodigestive ways. Most HNC are squamous cell carcinoma (SCCHN). Immunotherapy is a …
Lung cancer in never smokers: Tumor immunology and challenges for immunotherapy
Lung cancer is the second most common and the most lethal malignancy worldwide. It is
estimated that lung cancer in never smokers (LCINS) accounts for 10-25% of cases, and its …
estimated that lung cancer in never smokers (LCINS) accounts for 10-25% of cases, and its …