Molecular and anatomical organization of the dorsal raphe nucleus

KW Huang, NE Ochandarena, AC Philson, M Hyun… - Elife, 2019 - elifesciences.org
The dorsal raphe nucleus (DRN) is an important source of neuromodulators and has been
implicated in a wide variety of behavioral and neurological disorders. The DRN is …

Unraveling the architecture of the dorsal raphe synaptic neuropil using high-resolution neuroanatomy

M Soiza-Reilly, KG Commons - Frontiers in neural circuits, 2014 - frontiersin.org
The dorsal raphe nucleus (DRN), representing the main source of brain's serotonin, is
implicated in the pathophysiology and therapeutics of several mental disorders that can be …

Serotonergic modulation across sensory modalities

TR Sizemore, LM Hurley… - Journal of …, 2020 - journals.physiology.org
The serotonergic system has been widely studied across animal taxa and different functional
networks. This modulatory system is therefore well positioned to compare the consequences …

The effect of acute and chronic social stress on the hippocampal transcriptome in mice

AM Stankiewicz, J Goscik, A Majewska, AH Swiergiel… - PloS one, 2015 - journals.plos.org
Psychogenic stress contributes to the formation of brain pathology. Using gene expression
microarrays, we analyzed the hippocampal transcriptome of mice subjected to acute and …

Spatiotemporal patterns of gene expression around implanted silicon electrode arrays

CH Thompson, A Saxena, N Heelan… - Journal of neural …, 2021 - iopscience.iop.org
Objective. Intracortical brain interfaces are an ever evolving technology with growing
potential for clinical and research applications. The chronic tissue response to these devices …

Pet-1 switches transcriptional targets postnatally to regulate maturation of serotonin neuron excitability

SC Wyler, WC Spencer, NH Green, BD Rood… - Journal of …, 2016 - jneurosci.org
Newborn neurons enter an extended maturation stage, during which they acquire excitability
characteristics crucial for development of presynaptic and postsynaptic connectivity. In …

Depression-like behavior in rat: Involvement of galanin receptor subtype 1 in the ventral periaqueductal gray

P Wang, H Li, S Barde, MD Zhang, J Sun… - Proceedings of the …, 2016 - pnas.org
The neuropeptide galanin coexists in rat brain with serotonin in the dorsal raphe nucleus
and with noradrenaline in the locus coeruleus (LC), and it has been suggested to be …

[HTML][HTML] Serotonergic neuron regulation informed by in vivo single-cell transcriptomics

JM Spaethling, D Piel, H Dueck, PT Buckley… - The FASEB …, 2014 - pmc.ncbi.nlm.nih.gov
Despite the recognized importance of the dorsal raphe (DR) serotonergic (5-HT) nuclei in
the pathophysiology of depression and anxiety, the molecular components/putative drug …

Analysis of spatial-temporal gene expression patterns reveals dynamics and regionalization in develo** mouse brain

SJ Chou, C Wang, N Sintupisut, ZX Niou, CH Lin… - Scientific Reports, 2016 - nature.com
Abstract Allen Brain Atlas (ABA) provides a valuable resource of spatial/temporal gene
expressions in mammalian brains. Despite rich information extracted from this database …

Deletion of the P/Q-type calcium channel from serotonergic neurons drives male aggression in mice

P Bohne, A Volkmann, MK Schwarz… - Journal of …, 2022 - jneurosci.org
Aggressive behavior is one of the most conserved social interactions in nature and serves
as a crucial evolutionary trait. Serotonin (5-HT) plays a key role in the regulation of our …