Quercetin derivatives: Drug design, development, and biological activities, a review

SR Alizadeh, MA Ebrahimzadeh - European journal of medicinal chemistry, 2022 - Elsevier
More studies are needed to develop new drugs for problems associated with drug
resistance and unfavorable side effects. The natural flavonoid of quercetin revealed a wide …

[HTML][HTML] Advancement and prospects of bioinformatics analysis for studying bioactive peptides from food-derived protein: Sequence, structure, and functions

M Tu, S Cheng, W Lu, M Du - TrAC Trends in Analytical Chemistry, 2018 - Elsevier
Food-derived bioactive peptides, as potential ingredients in health-promoting functional
foods targeting diet-related chronic diseases, have attracted increasing attention because of …

Investigation of potential inhibitor properties of ethanolic propolis extracts against ACE-II receptors for COVID-19 treatment by molecular docking study

HI Guler, G Tatar, O Yildiz, AO Belduz, S Kolayli - Archives of microbiology, 2021 - Springer
The angiotensin-converting enzyme (ACE)-related carboxypeptidase, ACE-II, is a type I
integral membrane protein of 805 amino acids that contains 1 HEXXH-E zinc binding …

Polyphenol protection and treatment of hypertension

HM Hügel, N Jackson, B May, AL Zhang, CC Xue - Phytomedicine, 2016 - Elsevier
Introduction High blood pressure is the major risk factor for cardiovascular diseases and the
rising prevalence of human hypertension precedes the trend toward a global epidemic of …

[HTML][HTML] The effects of Allium cepa L.(onion) and its active constituents on metabolic syndrome: A review

A Galavi, H Hosseinzadeh… - Iranian journal of basic …, 2021 - ncbi.nlm.nih.gov
Metabolic syndrome as a clustering disorder includes excess abdominal fat distribution,
abnormal insulin and glucose metabolism, disturbed blood lipids, pro-inflammatory state …

Terpyridine-metal complexes: effects of different substituents on their physico-chemical properties and density functional theory studies

EU Mughal, M Mirzaei, A Sadiq… - Royal Society …, 2020 - royalsocietypublishing.org
A series of different substituted terpyridine (tpy)-based ligands have been synthesized by
Kröhnke method. Their binding behaviour was evaluated by complexing them with Co (II) …

Quantum chemical calculation, topological analysis, biological evaluation and molecular docking of allo‐ocimenol against breast cancer

K Chandran, A Zochedh, S Sukumaran… - … Journal of Quantum …, 2024 - Wiley Online Library
The main aim of this study is to identify the structural stability of allo‐ocimenol and its
molecular reactivity against breast cancer‐associated proteins to confirm its anti‐cancer …

Prediction of Bioactive Peptides from Chlorella sorokiniana Proteins Using Proteomic Techniques in Combination with Bioinformatics Analyses

LA Tejano, JP Peralta, EES Yap, FCA Panjaitan… - International Journal of …, 2019 - mdpi.com
Chlorella is one of the most nutritionally important microalgae with high protein content and
can be a good source of potential bioactive peptides. In the current study, isolated proteins …

[HTML][HTML] Network pharmacology based anti-diabetic attributes of bioactive compounds from Ocimum gratissimum L. through computational approach

RY Halayal, ZK Bagewadi, RB Maliger… - Saudi Journal of …, 2023 - Elsevier
The present research was framed to determine the key compounds present in the plant
Ocimum gratissimum L. targeting protein molecules of Diabetes Mellitus (DM) by employing …

Molecular Recognition of Moringa oleifera Active Compounds for Stunted Growth Prevention Using Network Pharmacology and Molecular Modeling Approach

A Arwansyah, AF Lewa, M Muliani, S Warnasih… - ACS …, 2023 - ACS Publications
In this study, network pharmacology was used to analyze the active compounds of Moringa
oleifera as food supplements for stunted growth prevention. Thirty-eight important proteins …