COVID-19 in pediatric populations

YK Okuducu, MA Mall… - Clinics in Chest …, 2024 - chestmed.theclinics.com
As the SARS-CoV-2 virus emerged and a global pandemic unfolded, adults filled
emergency rooms, hospital wards, and intensive care units while children appeared spared …

COVID-19 in children: Evolving epidemiology, immunology, symptoms, diagnostics, treatment, post covid conditions, prevention strategies, and future directions

J Wurm, N Ritz, P Zimmermann - Journal of Allergy and Clinical …, 2024 - Elsevier
The epidemiology of COVID-19 in children has evolved throughout the pandemic, with
initially low infection rates rising significantly due to the emergence of the more transmissible …

Hybrid response to SARS-CoV-2 and Neisseria meningitidis C after an OMV-adjuvanted immunization in mice and their offspring

AI Portilho, H Hermes Monteiro da Costa… - Human Vaccines & …, 2024 - Taylor & Francis
ABSTRACT COVID-19, caused by SARS-CoV-2, and meningococcal disease, caused by
Neisseria meningitidis, are relevant infectious diseases, preventable through vaccination …

Presentations and Outcomes Among Infants≤ 90 Days With and Without SARS-CoV-2

B Burstein, V Sabhaney, TA Florin, J **e… - …, 2024 - publications.aap.org
OBJECTIVES To compare symptoms and outcomes among infants aged≤ 90 days tested
for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a broad, international …

Six clinical phenotypes with prognostic implications were identified by unsupervised machine learning in children and adolescents with SARS-CoV-2 infection: results …

Y Shi, R Strobl, R Berner, J Armann, S Scheithauer… - Respiratory …, 2024 - Springer
Objective Phenotypes are important for patient classification, disease prognostication, and
treatment customization. We aimed to identify distinct clinical phenotypes of children and …

Interim safety and immunogenicity of COVID-19 omicron BA. 1 variant-containing vaccine in children in the USA: an open-label non-randomised phase 3 trial

A Dixit, R Bennett, K Ali, C Griffin, RA Clifford… - The Lancet Infectious …, 2024 - thelancet.com
Background Variant-containing mRNA vaccines for COVID-19 to broaden protection against
SARS-CoV-2 variants are recommended based on findings in adults. We report interim …

Humoral and cellular immune responses in vaccinated and unvaccinated children following SARS‐CoV‐2 Omicron infection

ZQ Toh, J Anderson, N Mazarakis… - Clinical & …, 2024 - Wiley Online Library
Objectives The immune response in children elicited by SARS‐CoV‐2 Omicron infection
alone or in combination with COVID‐19 vaccination (hybrid immunity) is poorly understood …

Characteristics and Clinical Outcomes of Vaccine-Eligible US Children Under-5 Years Hospitalized for Acute COVID-19 in a National Network

LD Zambrano, MM Newhams… - The Pediatric …, 2024 - journals.lww.com
Methods: We enrolled inpatients 8 months to< 5 years of age with acute community-acquired
COVID-19 across 28 US pediatric hospitals from September 20, 2022 to May 31, 2023. We …

Pediatric COVID-19 severity by SARS-CoV-2 lineage and vaccine status in Canada: an IMPACT study

DS Farrar, JA Bettinger, AJ Campigotto, SL Deeks… - Pediatric …, 2025 - nature.com
Background Interpretations of pediatric COVID-19 severity are complicated by novel
lineages and COVID-19 vaccine introduction. We estimated the risk of severe COVID-19 by …

How international guidelines recommend treating children who have severe COVID‐19 or risk disease progression

J Mańdziuk, E Kuchar, M Okarska‐Napierała - Acta Paediatrica, 2024 - Wiley Online Library
Aim This study reviewed the current knowledge and guidelines on managing COVID‐19 in
children and proposed a practical approach to drug treatment. Methods We analysed …