Higher-than-conventional radiation doses in localized prostate cancer treatment: a meta-analysis of randomized, controlled trials

GA Viani, EJ Stefano, SL Afonso - International Journal of Radiation …, 2009 - Elsevier
PURPOSE: To determine in a meta-analysis whether the outcomes in men with localized
prostate cancer treated with high-dose radiotherapy (HDRT) are better than those in men …

Targeted radiotherapy with gold nanoparticles: current status and future perspectives

W Ngwa, R Kumar, S Sridhar, H Korideck… - …, 2014 - Taylor & Francis
Radiation therapy (RT) is the treatment of cancer and other diseases with ionizing radiation.
The ultimate goal of RT is to destroy all the disease cells while sparing healthy tissue …

Comparison of conventional-dose vs high-dose conformal radiation therapy in clinically localized adenocarcinoma of the prostate: a randomized controlled trial

AL Zietman, ML DeSilvio, JD Slater, CJ Rossi… - Jama, 2005 - jamanetwork.com
ContextClinically localized prostate cancer is very prevalent among US men, but recurrence
after treatment with conventional radiation therapy is common. ObjectiveTo evaluate the …

ASCENDE-RT: an analysis of treatment-related morbidity for a randomized trial comparing a low-dose-rate brachytherapy boost with a dose-escalated external beam …

S Rodda, S Tyldesley, WJ Morris, M Keyes… - International Journal of …, 2017 - Elsevier
Purpose To report the genitourinary (GU) and gastrointestinal (GI) morbidity and erectile
dysfunction in a randomized trial comparing 2 methods of dose escalation for high-and …

Long-term outcome of high dose intensity modulated radiation therapy for patients with clinically localized prostate cancer

MJ Zelefsky, H Chan, M Hunt, Y Yamada… - The Journal of …, 2006 - auajournals.org
Purpose: We report on the long-term results and late toxicity outcomes of high dose intensity
modulated radiation therapy for patients with clinically localized prostate cancer. Materials …

Long-term results of conformal radiotherapy for prostate cancer: impact of dose escalation on biochemical tumor control and distant metastases-free survival outcomes

MJ Zelefsky, Y Yamada, Z Fuks, Z Zhang… - International Journal of …, 2008 - Elsevier
PURPOSE: To report prostate-specific antigen (PSA) relapse-free survival and distant
metastases–free survival (DMFS) outcomes for patients with clinically localized prostate …

Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells

C Cao, T Subhawong, JM Albert, KW Kim, L Geng… - Cancer research, 2006 - AACR
The phosphatidylinositol 3-kinase/Akt pathway plays a critical role in oncogenesis, and
dysregulation of this pathway through loss of PTEN suppression is a particularly common …

Comparison of localization performance with implanted fiducial markers and cone-beam computed tomography for on-line image-guided radiotherapy of the prostate

DJ Moseley, EA White, KL Wiltshire, T Rosewall… - International Journal of …, 2007 - Elsevier
Purpose: The aim of this work was to assess the accuracy of kilovoltage (kV) cone-beam
computed tomography (CBCT)–based setup corrections as compared with orthogonal …

Ultra-high dose (86.4 Gy) IMRT for localized prostate cancer: toxicity and biochemical outcomes

O Cahlon, MJ Zelefsky, A Shippy, H Chan… - International Journal of …, 2008 - Elsevier
PURPOSE: To report toxicity and preliminary biochemical outcomes with high-dose intensity-
modulated radiation therapy (IMRT) to a dose of 86.4 Gy for localized prostate cancer …

Ten‐year outcomes of high‐dose, intensity‐modulated radiotherapy for localized prostate cancer

ZA Alicikus, Y Yamada, Z Zhang, X Pei, M Hunt… - Cancer, 2011 - Wiley Online Library
BACKGROUND. The authors investigated long‐term tumor control and toxicity outcomes
after high‐dose, intensity‐modulated radiation therapy (IMRT) in patients who had clinically …