Wnt signaling in colorectal cancer: pathogenic role and therapeutic target

H Zhao, T Ming, S Tang, S Ren, H Yang, M Liu, Q Tao… - Molecular cancer, 2022 - Springer
Abstract Background The Wnt signaling pathway is a complex network of protein interactions
that functions most commonly in embryonic development and cancer, but is also involved in …

Phenolic phytochemicals for prevention and treatment of colorectal cancer: a critical evaluation of in vivo studies

S De, S Paul, A Manna, C Majumder, K Pal, N Casarcia… - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer (CRC) is a significant cause of death worldwide. The
inefficacy of the current treatment regimens is reflected in the frequent recurrence and …

Why does obesity as an inflammatory condition predispose to colorectal cancer?

AM Rychter, L Łykowska-Szuber, A Zawada… - Journal of Clinical …, 2023 - mdpi.com
Obesity is a complex and multifactorial problem of global importance. Additionally, obesity
causes chronic inflammation, upregulates cell growth, disturbs the immune system, and …

Chemoprevention effect of the Mediterranean diet on colorectal cancer: Current studies and future prospects

AI Mahmod, SK Haif, A Kamal, IA Al-Ataby… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is the third most common cancer and the second most deadly
cancer worldwide. Nevertheless, more than 70% of CRC cases are resulted from sporadic …

Hydroxytyrosol and its potential uses on intestinal and gastrointestinal disease

A Arangia, Y Marino, D Impellizzeri, R D'Amico… - International Journal of …, 2023 - mdpi.com
In recent years, the phytoconstituents of foods in the Mediterranean diet (MD) have been the
subject of several studies for their beneficial effects on human health. The traditional MD is …

Classification and antioxidant activity evaluation of edible oils by using nanomaterial-based electrochemical sensors

IG Munteanu, C Apetrei - International Journal of Molecular Sciences, 2023 - mdpi.com
The classification of olive oils and the authentication of their biological or geographic origin
are important issues for public health and for the olive oil market and related industries. The …

[HTML][HTML] Protective effects of olive oil antioxidant phenols on mercury-induced phosphatidylserine externalization in erythrocyte membrane: Insights into scramblase …

P Perrone, R Notariale, G Lettieri, L Mele… - Free Radical Biology …, 2025 - Elsevier
In several physiopathological processes, phosphatidylserine (PS), normally sequestered to
the inner leaflet of the plasma membrane, becomes exposed to the cell surface. In …

Harmony unveiled: Intricate the interplay of dietary factor, gut microbiota, and colorectal cancer—A narrative review

HT Endale, W Tesfaye, FS Hassen… - SAGE Open …, 2024 - journals.sagepub.com
Diet plays a critical role in sha** the gut microbiome, which in turn regulates molecular
activities in the colonic mucosa. The state and composition of the gut microbiome are key …

[HTML][HTML] The Olive Oil Phenolic S-(-)-Oleocanthal Suppresses Colorectal Cancer Progression and Recurrence by Modulating SMYD2-EZH2 and c-MET Activation

MTI Tarun, HE Elsayed, HY Ebrahim, KA El Sayed - Nutrients, 2025 - mdpi.com
Background/Objectives: Colorectal cancer (CRC) is the third most common cancer in the US
and the second leading cancer-associated mortality cause. Available CRC therapies …

Mushrooms and Colorectal Cancer: Unveiling Mechanistic Insights and Therapeutic Innovations

S Kurl, S Kaur, N Mittal, G Kaur - Phytotherapy Research, 2025 - Wiley Online Library
Nature has bestowed us with an abundant reservoir of resources that besides having
nutritional value, are prolific mines of bioactive constituents with a plethora of medicinal …