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Long non-coding RNAs: definitions, functions, challenges and recommendations
Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …
Advances and trends in omics technology development
X Dai, L Shen - Frontiers in Medicine, 2022 - frontiersin.org
The human history has witnessed the rapid development of technologies such as high-
throughput sequencing and mass spectrometry that led to the concept of “omics” and …
throughput sequencing and mass spectrometry that led to the concept of “omics” and …
NCBI GEO: archive for gene expression and epigenomics data sets: 23-year update
E Clough, T Barrett, SE Wilhite, P Ledoux… - Nucleic acids …, 2024 - academic.oup.com
Abstract The Gene Expression Omnibus (GEO) is an international public repository that
archives gene expression and epigenomics data sets generated by next-generation …
archives gene expression and epigenomics data sets generated by next-generation …
Gene regulation by long non-coding RNAs and its biological functions
Evidence accumulated over the past decade shows that long non-coding RNAs (lncRNAs)
are widely expressed and have key roles in gene regulation. Recent studies have begun to …
are widely expressed and have key roles in gene regulation. Recent studies have begun to …
Deciphering molecular interactions by proximity labeling
Many biological processes are executed and regulated through the molecular interactions of
proteins and nucleic acids. Proximity labeling (PL) is a technology for tagging the …
proteins and nucleic acids. Proximity labeling (PL) is a technology for tagging the …
The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity
J Liu, M Gao, J He, K Wu, S Lin, L **, Y Chen, H Liu… - Nature, 2021 - nature.com
The RNA modification N 6-methyladenosine (m6A) has critical roles in many biological
processes,. However, the function of m6A in the early phase of mammalian development …
processes,. However, the function of m6A in the early phase of mammalian development …
Cellular functions of long noncoding RNAs
A diverse catalog of long noncoding RNAs (lncRNAs), which lack protein-coding potential,
are transcribed from the mammalian genome. They are emerging as important regulators in …
are transcribed from the mammalian genome. They are emerging as important regulators in …
Functional classification and experimental dissection of long noncoding RNAs
Over the last decade, it has been increasingly demonstrated that the genomes of many
species are pervasively transcribed, resulting in the production of numerous long noncoding …
species are pervasively transcribed, resulting in the production of numerous long noncoding …
METTL3 regulates heterochromatin in mouse embryonic stem cells
Abstract METTL3 (methyltransferase-like 3) mediates the N 6-methyladenosine (m6A)
methylation of mRNA, which affects the stability of mRNA and its translation into protein …
methylation of mRNA, which affects the stability of mRNA and its translation into protein …
The functions and unique features of long intergenic non-coding RNA
Long intergenic non-coding RNA (lincRNA) genes have diverse features that distinguish
them from mRNA-encoding genes and exercise functions such as remodelling chromatin …
them from mRNA-encoding genes and exercise functions such as remodelling chromatin …