Targeting molecular mediators of ferroptosis and oxidative stress for neurological disorders

J Li, B Jia, Y Cheng, Y Song, Q Li… - Oxidative Medicine and …, 2022 - Wiley Online Library
With the acceleration of population aging, nervous system diseases including Alzheimer's
disease (AD), Parkinson's disease (PD), Huntington's disease (HD), anxiety, depression …

Cdk5 and aberrant cell cycle activation at the core of neurodegeneration

R Requejo-Aguilar - Neural Regeneration Research, 2023 - journals.lww.com
Neurodegenerative diseases are caused by the progressive loss of specific neurons. The
exact mechanisms of action of these diseases are unknown, and many studies have focused …

Nano-hydroxyapatite and ZnO-NPs mitigate Pb stress in maize

BA Alhammad, A Ahmad, MF Seleiman - Agronomy, 2023 - mdpi.com
Heavy metals (HMs) stress, particularly lead (Pb) stress, is one of the most hazardous
environmental stresses that can negatively affect plants' growth, yield, and quality …

Diamond relaxometry as a tool to investigate the free radical dialogue between macrophages and bacteria

K Wu, L Nie, AC Nusantara, W Woudstra, T Vedelaar… - ACS …, 2023 - ACS Publications
Although free radicals, which are generated by macrophages play a key role in antimicrobial
activities, macrophages sometimes fail to kill Staphylococcus aureus (S. aureus) as bacteria …

Ferroptosis: underlying mechanisms and involvement in neurodegenerative diseases

Y Wang, HJ Li, QX He, R Zou, JR Cai, L Zhang - Apoptosis, 2024 - Springer
Ferroptosis, a mode of cell death that was recently identified in 2012, is driven by iron-
dependent lipid peroxidation and distinct from other mechanisms of cell death such as …

Protective Effects and Mechanisms of Pectolinarin against H2O2-Induced Oxidative Stress in SH-SY5Y Neuronal Cells

QQ Pang, JH Kim, HY Kim, JH Kim, EJ Cho - Molecules, 2023 - mdpi.com
This study aims to investigate the protective effects and mechanisms of pectolinarin against
oxidative stress-induced cell damage in SH-SY5Y cells. Neurodegenerative diseases—such …

Coumarin hybrids for targeted therapies: A promising approach for potential drug candidates

NM Zeki, YF Mustafa - Phytochemistry Letters, 2024 - Elsevier
Phyto-coumarins demonstrate diverse biological actions, encompassing antiradical, anti-
inflammatory, oncolytic, monoamine oxidase B (MAOB) suppression, and antibacterial …

Mechanistic elucidation of ferroptosis and ferritinophagy: implications for advancing our understanding of arthritis

C Guo, J Peng, P Cheng, C Yang, S Gong… - Frontiers in …, 2024 - frontiersin.org
In recent years, the emerging phenomenon of ferroptosis has garnered significant attention
as a distinctive mode of programmed cell death. Distinguished by its reliance on iron and …

Solvent based fractional biosynthesis, phytochemical analysis, and biological activity of silver nanoparticles obtained from the extract of Salvia moorcroftiana

M Khan, T Khan, S Wahab, M Aasim, TA Sherazi… - Plos one, 2023 - journals.plos.org
Multi-drug resistant bacteria sometimes known as “superbugs” developed through overuse
and misuse of antibiotics are determined to be sensitive to small concentrations of silver …

Nutraceutical potential of olive pomace: insights from cell‐based and clinical studies

CSA Monteiro, IA Adedara, EO Farombi… - Journal of the …, 2024 - Wiley Online Library
Olive oil production yields a substantial volume of by‐products, constituting up to 80% of the
processed fruits. The olive pomace by‐product represents a residue of significant interest …