Lessons from the deep: mechanisms behind diversification of eukaryotic protein complexes

G Prokopchuk, A Butenko, JB Dacks… - Biological …, 2023 - Wiley Online Library
Genetic variation is the major mechanism behind adaptation and evolutionary change. As
most proteins operate through interactions with other proteins, changes in protein complex …

Anaerobic ciliates as a model group for studying symbioses in oxygen‐depleted environments

J Rotterová, VP Edgcomb, I Čepička… - Journal of Eukaryotic …, 2022 - Wiley Online Library
Anaerobiosis has independently evolved in multiple lineages of ciliates, allowing them to
colonize a variety of anoxic and oxygen‐depleted habitats. Anaerobic ciliates commonly …

Adaptation of the late ISC pathway in the anaerobic mitochondrial organelles of Giardia intestinalis

A Motyčková, L Voleman, V Najdrová… - PLoS …, 2023 - journals.plos.org
Mitochondrial metabolism is entirely dependent on the biosynthesis of the [4Fe-4S] clusters,
which are part of the subunits of the respiratory chain. The mitochondrial late ISC pathway …

Anaerocyclidiidae fam. nov.(Oligohymenophorea, Scuticociliatia): A newly recognized major lineage of anaerobic ciliates hosting prokaryotic symbionts

K Poláková, WA Bourland, I Čepička - European Journal of Protistology, 2023 - Elsevier
The research on anaerobic ciliates, to date, has mainly been focused on representatives of
obligately anaerobic classes such as Armophorea or Plagiopylea. In this study, we focus on …

Inheritance of the reduced mitochondria of Giardia intestinalis is coupled to the flagellar maturation cycle

P Tůmová, L Voleman, A Klingl, E Nohýnková… - BMC biology, 2021 - Springer
Background The presence of mitochondria is a distinguishing feature between prokaryotic
and eukaryotic cells. It is currently accepted that the evolutionary origin of mitochondria …

Evidence for an independent hydrogenosome-to-mitosome transition in the CL3 lineage of fornicates

R Vargová, P Hanousková, J Salamonová… - Frontiers in …, 2022 - frontiersin.org
Fornicata, a lineage of a broader and ancient anaerobic eukaryotic clade Metamonada,
contains diverse taxa that are ideally suited for evolutionary studies addressing various …

Characterization of Skoliomonas gen. nov., a haloalkaliphilic anaerobe related to barthelonids (Metamonada)

Y Eglit, SK Williams, AJ Roger… - Journal of Eukaryotic …, 2024 - Wiley Online Library
Metamonads are a large and exclusively anaerobic group of protists. Additionally, they are
one of the three clades proposed to ancestrally possess an “excavate” cell morphology, with …

Vestiges of the bacterial signal recognition particle-based protein targeting in mitochondria

J Pyrih, T Pánek, IM Durante, V Rašková… - Molecular biology …, 2021 - academic.oup.com
The main bacterial pathway for inserting proteins into the plasma membrane relies on the
signal recognition particle (SRP), composed of the Ffh protein and an associated RNA …

The late ISC pathway interactome reveals mitosomal-cytoplasmic crosstalk in Giardia intestinalis

A Motyčková, L Voleman, V Najdrová, L Marková… - bioRxiv, 2022 - biorxiv.org
Mitochondrial metabolism is entirely dependent on the biosynthesis of the [4Fe-4S] clusters,
which are part of the subunits of the respiratory chain. The mitochondrial late ISC pathway …

Two newly cultivated eukaryotrophic flagellates represent distinct anaerobic lineages

Y Eglit, M Lawton, AGB Simpson, RMR Gawryluk - bioRxiv, 2024 - biorxiv.org
Endomyxans are a poorly sampled and incompletely resolved aggregate of Rhizarian
lineages that fall outside Filosa and Retaria. Among them," Novel Clade 12"(NC12; Bass et …