Acid‐sensing ion channels (ASICs) are a class of trimeric cation‐selective ion channels
activated by changes in pH within the physiological range. They are widely expressed in the …

Traumatic events generate some of the most enduring memories, yet little is known about
how long-lasting fear memories can be attenuated. In this review, we collect the surprisingly …

Heat perception enables acute avoidance responses to prevent tissue damage and
maintain body thermal homeostasis. Unlike other modalities, how heat signals are …

Acid-sensing ion channels (ASICs) are mainly proton-gated cation channels that are
activated by pH drops and nonproton ligands. They are part of the degenerin/epithelial …

Acid‐sensing ion channels (ASICs) are important players in detecting extracellular
acidification throughout the brain and body. ASICs have large extracellular domains …

Social dominance is essential for maintaining a stable society and has both positive and
negative impacts on social animals, including humans. However, the regulatory …

Acid-sensing ion channels (ASICs) are proton-gated cation channels that contribute to fast
synaptic transmission and have roles in fear conditioning and nociception. Apart from …

Fear conditioning is widely employed to study dysregulations of the fear system. The
repeated presentation of a conditioned stimulus in the absence of a reinforcer leads to a …

Brain acid signaling plays important roles in both physiological and disease conditions. One
key neuronal metabotropic proton receptor in the brain is GPR68, which contributes to …

Memory reconsolidation is hypothesized to be a mechanism by which memories can be
updated with new information. Such updating has previously been shown to weaken …