Nanoprecipitation and the “Ouzo effect”: Application to drug delivery devices

E Lepeltier, C Bourgaux, P Couvreur - Advanced drug delivery reviews, 2014 - Elsevier
Biodegradable nanocarriers such as lipid-or polymer-based nanoparticles can be designed
to improve the efficacy and reduce the toxic side effects of drugs. Under appropriate …

[HTML][HTML] Application of flash nanoprecipitation to fabricate poorly water-soluble drug nanoparticles

J Tao, SF Chow, Y Zheng - Acta pharmaceutica sinica B, 2019 - Elsevier
Nanoparticles are considered to be a powerful approach for the delivery of poorly water-
soluble drugs. One of the main challenges is develo** an appropriate method for …

Formulation of nanoparticles using mixing-induced nanoprecipitation for drug delivery

Y Liu, G Yang, D Zou, Y Hui, K Nigam… - Industrial & …, 2019 - ACS Publications
Significant efforts have been made to fabricate drug-loaded nanoparticles for drug delivery.
Nanoprecipitation is a simple and versatile method for making various types of polymer …

Using microfluidics for scalable manufacturing of nanomedicines from bench to GMP: A case study using protein-loaded liposomes

C Webb, N Forbes, CB Roces, G Anderluzzi… - International Journal of …, 2020 - Elsevier
Nanomedicines are well recognised for their ability to improve therapeutic outcomes. Yet,
due to their complexity, nanomedicines are challenging and costly to produce using …

Microfluidics for pharmaceutical nanoparticle fabrication: The truth and the myth

SI Hamdallah, R Zoqlam, P Erfle, M Blyth… - International journal of …, 2020 - Elsevier
Using micro-sized channels to manipulate fluids is the essence of microfluidics which has
wide applications from analytical chemistry to material science and cell biology research …

Toward the scale-up production of polymeric nanotherapeutics for cancer clinical trials

MM Mahmud, N Pandey, JA Winkles, GF Woodworth… - Nano Today, 2024 - Elsevier
Nanotherapeutics have gained significant attention for the treatment of numerous cancers,
primarily because they can accumulate in and/or selectively target tumors leading to …

Microfluidic and lab-on-a-chip preparation routes for organic nanoparticles and vesicular systems for nanomedicine applications

L Capretto, D Carugo, S Mazzitelli, C Nastruzzi… - Advanced drug delivery …, 2013 - Elsevier
In recent years, advancements in the fields of microfluidic and lab-on-a-chip technologies
have provided unique opportunities for the implementation of nanomaterial production …

Microfluidics based manufacture of liposomes simultaneously entrap** hydrophilic and lipophilic drugs

S Joshi, MT Hussain, CB Roces, G Anderluzzi… - International journal of …, 2016 - Elsevier
Despite the substantial body of research investigating the use of liposomes, niosomes and
other bilayer vesicles for drug delivery, the translation of these systems into licensed …

[HTML][HTML] High-throughput manufacturing of size-tuned liposomes by a new microfluidics method using enhanced statistical tools for characterization

E Kastner, R Kaur, D Lowry, B Moghaddam… - International journal of …, 2014 - Elsevier
Microfluidics has recently emerged as a new method of manufacturing liposomes, which
allows for reproducible mixing in miliseconds on the nanoliter scale. Here we investigate …

Nanoprecipitation process: from particle preparation to in vivo applications

K Miladi, S Sfar, H Fessi, A Elaissari - … for Nanomedicines: A Guide for their …, 2016 - Springer
Nanoparticles have been widely prepared during the past decades. In fact, encapsulation
could provide several advantages over conventional pharmaceutical forms (Miladi et al. in …